Trial · NCT07888543
Study of the Link Between Structural Alterations in the Hypothalamus and Cardiac Dysautonomia in Drug-resistant Epilepsy
NCT07888543, Not applicable, Recruiting, Centre Hospitalier Universitaire, Amiens
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Study of the Link Between Structural Alterations in the Hypothalamus and Cardiac Dysautonomia in Drug-resistant Epilepsy. Trials, record NCT07888543. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07888543
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Study of the Link Between Structural Alterations in the Hypothalamus and Cardiac Dysautonomia in Drug-resistant Epilepsy
- NCT number
- NCT07888543
- Status
- Recruiting
- Phases
- Not applicable
- Enrollment
- 20 participants, estimated
- Lead sponsor
- Centre Hospitalier Universitaire, Amiens
- Conditions
- Epilepsy, Hypothalamus, Seizures- Cardiac Dysautonomia, SUDEP
- Interventions
- MRI scan, electrocardiogram
- First posted
- 2026-10-22
- Last updated
- 2026-10-22
Source ClinicalTrials.gov
Registered outcomes11
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Correlation coefficient between the volume of the posterior hypothalamic nucleus with the degree of cardiac autonomic function impairment | 5 months | Correlation coefficient between the volume of the posterior hypothalamic nucleus with the degree of cardiac autonomic function impairment across the entire cohort of patients with epilepsy |
| Secondary | correlation of anterior nucleus volumes with HRV parameters | 5 months | correlation of anterior nucleus volumes with HRV parameters. HRV is heart rate variability. HRV, which is calculated from the intervals between normal heart beats |
| Secondary | correlation of lateral nucleus volumes with HRV parameters | 5 months | correlation of lateral nucleus volumes with HRV parameters HRV is heart rate variability. HRV, which is calculated from the intervals between normal heart beats |
| Secondary | correlation of the posterior nucleus volumes with the risk of SUDEP | 5 months | correlation of the posterior nucleus volumes with the risk of SUDEP |
| Secondary | correlation of the lateral nucleus volumes with the risk of SUDEP | 5 months | correlation of the lateral nucleus volumes with the risk of SUDEP |
| Secondary | correlation of the anterior nucleus volumes with the risk of SUDEP | 5 months | correlation of the anterior nucleus volumes with the risk of SUDEP |
| Secondary | correlation of structural connectivity values with heart rate variability parameters | 5 months | Correlation of the structural connectivity values (amygdalo-hypothalamic tract, hypothalamo-bulbar tract, and intra-hypothalamic connectivity) with heart rate variability parameters. HRV is heart rate variability. HRV, which is calculated from the intervals between normal heart beats |
| Secondary | Correlation of metabolic values of the hypothalamus and the bulbar region with heart rate variability parameters | 5 months | Correlation of metabolic values of the hypothalamus and the bulbar region with heart rate variability parameters HRV is heart rate variability. HRV, which is calculated from the intervals between normal heart beats |
| Secondary | Correlation of the posterior nucleus volumes with the frequency of generalized seizures during the 12 months prior to enrollment | 5 months | Correlation of the posterior nucleus volumes with the frequency of generalized seizures during the 12 months prior to enrollment |
| Secondary | Correlation of the anterior nucleus volumes with the frequency of generalized seizures during the 12 months prior to enrollment | 5 months | Correlation of the anterior nucleus volumes with the frequency of generalized seizures during the 12 months prior to enrollment |
1 to 10 of 11Source ClinicalTrials.gov
See all 11 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07888543
GET https://conductscience.org/api/trials/v1/NCT07888543/registered