Trial · NCT07888868
Service Evaluation for Newborn Screening for Spinal Muscular Atrophy
NCT07888868, Recruiting, University of Oxford
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Service Evaluation for Newborn Screening for Spinal Muscular Atrophy. Trials, record NCT07888868. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07888868
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Service Evaluation for Newborn Screening for Spinal Muscular Atrophy
- NCT number
- NCT07888868
- Status
- Recruiting
- Enrollment
- 750,000 participants, estimated
- Lead sponsor
- University of Oxford
- Conditions
- Spinal Muscular Atrophy (SMA)
- First posted
- 2026-10-22
- Last updated
- 2026-10-22
Source ClinicalTrials.gov
Registered outcomes7
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Primary | Report: January 2031 | Number of patients born during the stepped wedge treated before 42 days of life. |
| Secondary | Secondary 1 | Report: March 2028 | Number of patients diagnosed during the stepped wedge treated before 42 days of life. |
| Secondary | Secondary 2 | Report: March 2028 | Age at diagnosis, age at treatment and time to treatment will be described as a continuous/ time-to-event outcome |
| Secondary | Secondary 3 | Report: March 2028 | Proportion of results delivered within 3 working days. |
| Secondary | Secondary 4 | Report: March 2028, January 2031 | Sensitivity, specificity, positive predictive value, and negative predictive value of SMA NBS |
| Secondary | Secondary 5 | Report: March 2028 | Proportion of approached parent(s)/guardians consenting to SMA NBS out of all those approached. |
| Secondary | Secondary 6 | Report: December 2028 January 2031 | Reasons for screening decline including barriers/facilitators of access. Comparison of demographic data between accepting and declining groups. Parent(s)/guardians and healthcare professionals' experiences of SMA NBS. Shared parent(s)/guardianal viewpoints on the acceptability of SMA NBS (Work Package 2 (WP2)). Recommendations for improving the acceptability of SMA NBS (WP2). |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07888868
GET https://conductscience.org/api/trials/v1/NCT07888868/registered