Trial · NCT07888998
Evaluation of the Effect of a Low-FODMAP Diet on Gastrointestinal Symptoms and Inflammatory Markers in Fabry Patients
NCT07888998, Not applicable, Active not recruiting, Acibadem University
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Evaluation of the Effect of a Low-FODMAP Diet on Gastrointestinal Symptoms and Inflammatory Markers in Fabry Patients. Trials, record NCT07888998. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07888998
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Evaluation of the Effect of a Low-FODMAP Diet on Gastrointestinal Symptoms and Inflammatory Markers in Fabry Patients
- NCT number
- NCT07888998
- Status
- Active not recruiting
- Phases
- Not applicable
- Enrollment
- 30 participants, estimated
- Lead sponsor
- Acibadem University
- Conditions
- Fabry Disease
- Interventions
- Low-FODMAP Diet
- First posted
- 2026-10-22
- Last updated
- 2026-10-26
Source ClinicalTrials.gov
Registered outcomes8
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change in Gastrointestinal Symptom Rating Scale (GSRS) Score | Baseline and Week 6 | Gastrointestinal symptoms will be evaluated using the Gastrointestinal Symptom Rating Scale (GSRS). The GSRS assesses gastrointestinal symptoms across five domains: abdominal pain, reflux, indigestion, diarrhea, and constipation. Each item is scored on a seven-point Likert scale, with higher scores indicating more severe gastrointestinal symptoms. Changes in GSRS scores from baseline to week 6 will be compared between the intervention and control groups. |
| Primary | Change in Plasma Neopterin Levels | Baseline and Week 6 | Neopterin levels will be measured at baseline and after six weeks to evaluate changes in inflammatory status. Changes from baseline will be compared between the intervention and control groups. |
| Primary | Change in Interleukin-6 (IL-6) Levels | Baseline and Week 6 | Interleukin-6 (IL-6) concentrations will be measured at baseline and after six weeks to evaluate changes in systemic inflammation following the dietary intervention. Changes in IL-6 concentrations from baseline to week 6 will be compared between the low-FODMAP diet and control groups. |
| Primary | Change in Tumor Necrosis Factor-alpha (TNF-α) Levels | Baseline and Week 6 | Tumor necrosis factor-alpha (TNF-α) concentrations will be measured at baseline and after six weeks to evaluate changes in systemic inflammation following the dietary intervention. Changes in TNF-α concentrations from baseline to week 6 will be compared between the low-FODMAP diet and control groups. |
| Primary | Change in Plasma Biopterin Levels | Baseline and Week 6 | Biopterin levels will be measured at baseline and after six weeks. Changes from baseline will be compared between the intervention and control groups. |
| Secondary | Change in Short Form-36 (SF-36) Health Survey Scores | Baseline and Week 6 | Health-related quality of life will be assessed using the 36-Item Short Form Health Survey (SF-36). The questionnaire evaluates eight domains of physical and mental health. Domain scores range from 0 to 100, with higher scores indicating better health-related quality of life. Changes from baseline to week 6 will be compared between the intervention and control groups. |
| Secondary | Change in Bristol Stool Form Scale Classification | Baseline and Week 6 | Stool consistency will be assessed using the Bristol Stool Form Scale, which categorizes stool characteristics into seven types (Type 1-7). Changes in stool characteristics between baseline and week 6 will be evaluated. |
| Secondary | Change in Lyso-Globotriaosylceramide (Lyso-Gb3) Levels | Baseline and Week 6 | Lyso-globotriaosylceramide (Lyso-Gb3) concentrations will be measured at baseline and after six weeks. Changes from baseline will be compared between the intervention and control groups. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers3
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07888998
GET https://conductscience.org/api/trials/v1/NCT07888998/registered