Trial · NCT07890064
Canagliflozin Plus Progestin for Atypical Endometrial Hyperplasia and Early-Stage Endometrial Cancer
NCT07890064, Phase 2, Not yet recruiting, Wang Yingmei
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Canagliflozin Plus Progestin for Atypical Endometrial Hyperplasia and Early-Stage Endometrial Cancer. Trials, record NCT07890064. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07890064
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Canagliflozin Plus Progestin for Atypical Endometrial Hyperplasia and Early-Stage Endometrial Cancer
- NCT number
- NCT07890064
- Status
- Not yet recruiting
- Phases
- Phase 2
- Enrollment
- 102 participants, estimated
- Lead sponsor
- Wang Yingmei
- Conditions
- Endometrioid Endometrial Cancer, Atypical Endometrial Hyperplasia
- Interventions
- LNG-IUS: levonorgestrel intrauterine system, Metformin, Canagliflozin
- First posted
- 2026-10-22
- Last updated
- 2026-10-22
Source ClinicalTrials.gov
Registered outcomes9
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Complete remission (CR) rate of endometrial lesions at 24 weeks | 24 weeks after treatment initiation | |
| Secondary | Complete remission (CR) rate of endometrial lesions at 12 weeks | 12 weeks after treatment initiation | |
| Secondary | Time to achieve complete remission (CR) | From treatment initiation up to 2 years | |
| Secondary | Cumulative CR rate | From treatment initiation up to 2 years | |
| Secondary | Recurrence-free rate among participants achieving CR | From achievement of CR up to 2 years | |
| Secondary | Recurrence-free interval among participants achieving CR | From achievement of CR up to 2 years | |
| Secondary | Pregnancy rate | From achievement of CR up to 2 years | Assessed among participants attempting pregnancy during the 2-year follow-up period. |
| Secondary | live birth rate | From achievement of CR up to 2 years | Assessed among participants attempting pregnancy during the 2-year follow-up period. |
| Secondary | Incidence of adverse events (AEs) and serious adverse events (SAEs) | From treatment initiation to completion |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07890064
GET https://conductscience.org/api/trials/v1/NCT07890064/registered