Trial · NCT07890987
VISION Study: Visualization-Guided SMAS Treatment to Optimize Nonsurgical Lifting
NCT07890987, Not applicable, Recruiting, Ocean Clinic
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. VISION Study: Visualization-Guided SMAS Treatment to Optimize Nonsurgical Lifting. Trials, record NCT07890987. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07890987
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- VISION Study: Visualization-Guided SMAS Treatment to Optimize Nonsurgical Lifting
- NCT number
- NCT07890987
- Status
- Recruiting
- Phases
- Not applicable
- Enrollment
- 50 participants, estimated
- Lead sponsor
- Ocean Clinic
- Conditions
- Facial Skin Laxity
- Interventions
- Microfocused Ultrasound with Visualization (MFU-V), multi Microfocused Ultrasound with Visualization (MFU-V)
- First posted
- 2026-10-23
- Last updated
- 2026-10-23
Source ClinicalTrials.gov
Registered outcomes12
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change in SMAS/Fibromuscular Layer Firmness | Baseline and Day 180 | Difference between baseline and Day 180 in SMAS/fibromuscular layer stiffness measured using Shear-Wave Elastography. |
| Secondary | Change From Baseline in Facial Soft-Tissue Displacement Measured by Vectra 3D Imaging | Baseline, Day 90, and Day 180 | Facial tissue displacement, in millimeters (mm), measured by three-dimensional imaging with the Vectra 3D system (Canfield Scientific), compared between the single-depth (1.5 mm) side and the multi-depth side. Time Frame : Baseline, Day 90, and Day 180 |
| Secondary | changes in dermal thickness | Baseline and Day 180 | Histologic evaluation of treatment-induced change in dermal thickness. Unit of Measure: millimeters (mm) |
| Secondary | Change in Skin elasticity measured by ElastiMeter | Baseline, Day 90, and Day 180 | Instant skin elasticity (ISE), expressed in newtons per meter (N/m), measured by indentation with the ElastiMeter (Delfin Technologies) on each side of the face. Higher values indicate greater tissue resistance to indentation. Compared between the single-depth (1.5 mm) side and the multi-depth side. |
| Secondary | Change in collagen type I regeneration | Baseline and Day 180 | Histologic evaluation of collagen type I regeneration measured by immunohistochemistry, expressed as the percentage of collagen-I-positive area relative to total tissue area. Unit of Measure: % positive area |
| Secondary | Change in collagen type III regeneration | Baseline and Day 180 | Histologic evaluation of collagen type III regeneration measured by immunohistochemistry, expressed as the percentage of collagen-III-positive area relative to total tissue area. Unit of Measure: % positive area |
| Secondary | Change in elastin regeneration | Baseline and Day 180 | Histologic evaluation of elastin regeneration measured by elastin-specific staining/immunohistochemistry, expressed as the percentage of elastin-positive area relative to total tissue area. Unit of Measure: % positive area |
| Secondary | Change in proteoglycan content | Baseline and Day 180 | Histologic evaluation of proteoglycan content measured by Alcian Blue/Safranin O staining or proteoglycan-specific immunohistochemistry, expressed as the percentage of stained area relative to total tissue area. Unit of Measure: % positive area |
| Secondary | Change in collagen fiber alignment | baseline and day 180 | image-analysis-derived collagen fiber coherence/alignment, expressed as an orientation index ranging from 0 (random alignment) to 1 (perfect alignment). Unit of Measure: orientation index (0-1), dimensionless |
| Secondary | Change in elastin fiber alignment | Baseline and day 180 | Image-analysis-derived elastin fiber coherence/alignment, expressed as an orientation index ranging from 0 (random alignment) to 1 (perfect alignment). Unit of Measure: orientation index (0-1), dimensionless |
1 to 10 of 12Source ClinicalTrials.gov
See all 12 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 38773827 | BACKGROUND |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07890987
GET https://conductscience.org/api/trials/v1/NCT07890987/registered