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Trial · NCT07891273

Beyond Voluntary Effort: Reliability and Validity of Magnetic Femoral Nerve Stimulation for Assessing Quadriceps Strength in Critically Ill Patient

NCT07891273, Not applicable, Not yet recruiting, Daniel Langer

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Beyond Voluntary Effort: Reliability and Validity of Magnetic Femoral Nerve Stimulation for Assessing Quadriceps Strength in Critically Ill Patient. Trials, record NCT07891273. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07891273

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Beyond Voluntary Effort: Reliability and Validity of Magnetic Femoral Nerve Stimulation for Assessing Quadriceps Strength in Critically Ill Patient
NCT number
NCT07891273
Status
Not yet recruiting
Phases
Not applicable
Enrollment
33 participants, estimated
Lead sponsor
Daniel Langer
Conditions
Critical Illness, ICU-acquired Weakness
Interventions
Magnetic Femoral Nerve Stimulation
First posted
2026-10-23
Last updated
2026-10-23

Source ClinicalTrials.gov

Registered outcomes8

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryIntra-rater reliability of paired quadriceps twitch force measurementsDay 1 and Day 2 (two consecutive days)
Intra-rater reliability of paired quadriceps twitch force measurements will be assessed using the intraclass correlation coefficient (ICC) with 95% confidence intervals, comparing measurements performed by the same assessor on two consecutive days. Measurement error and agreement will additionally be evaluated using the standard error of measurement (SEM), minimal detectable change (MDC95), and Bland-Altman analysis.
SecondaryInter-rater reliability of paired quadriceps twitch force measurementsDay 2 (morning and afternoon)
Inter-rater reliability of paired quadriceps twitch force measurements will be assessed using the intraclass correlation coefficient (ICC) with 95% confidence intervals, comparing measurements performed by two different assessors on the second day. Measurement error and agreement will additionally be evaluated using SEM, MDC95, and Bland-Altman analysis.
SecondaryIntra-rater reliability of single quadriceps twitch force measurementsDay 1 and Day 2 (two consecutive days)
Intra-rater reliability of single quadriceps twitch force measurements will be assessed using the intraclass correlation coefficient (ICC) with 95% confidence intervals, comparing measurements performed by the same assessor on two consecutive days. Measurement error and agreement will additionally be evaluated using SEM, MDC95, and Bland-Altman analysis.
SecondaryInter-rater reliability of single quadriceps twitch force measurementsDay 2 (morning and afternoon)
Inter-rater reliability of single quadriceps twitch force measurements will be assessed using the intraclass correlation coefficient (ICC) with 95% confidence intervals, comparing measurements performed by two different assessors on the second day. Measurement error and agreement will additionally be evaluated using SEM, MDC95, and Bland-Altman analysis.
SecondaryConvergent validity of single twitch force with maximal voluntary contractionDay 1
Convergent validity will be assessed by examining the association between single quadriceps twitch force measurements obtained using magnetic femoral nerve stimulation and maximal voluntary contraction (MVC) force, using Pearson's correlation coefficient (r).
SecondaryConvergent validity of paired twitch force with maximal voluntary contractionDay 1
Convergent validity will be assessed by examining the association between paired quadriceps twitch force measurements obtained using magnetic femoral nerve stimulation and maximal voluntary contraction (MVC) force, using Pearson's correlation coefficient (r).
SecondaryConvergent validity of single twitch force with potentiated twitch forceDay 1
Convergent validity will be assessed by examining the association between single quadriceps twitch force measurements obtained using magnetic femoral nerve stimulation and potentiated twitch force, using Pearson's correlation coefficient (r).
SecondaryConvergent validity of paired twitch force with potentiated twitch forceDay 1
Convergent validity will be assessed by examining the association between paired quadriceps twitch force measurements obtained using magnetic femoral nerve stimulation and potentiated twitch force, using Pearson's correlation coefficient (r).

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers0

The papers the trial lists on ClinicalTrials.gov.

None in this release.

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT07891273

GET https://conductscience.org/api/trials/v1/NCT07891273/registered