Trial · NCT07892495
The Clinical Efficacy and Multimodal Imaging Mechanism of the Knot-tying Technique in the Treatment of Chronic Neck Pain
NCT07892495, Not applicable, Not yet recruiting, Li Juntao
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. The Clinical Efficacy and Multimodal Imaging Mechanism of the Knot-tying Technique in the Treatment of Chronic Neck Pain. Trials, record NCT07892495. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07892495
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- The Clinical Efficacy and Multimodal Imaging Mechanism of the Knot-tying Technique in the Treatment of Chronic Neck Pain
- NCT number
- NCT07892495
- Status
- Not yet recruiting
- Phases
- Not applicable
- Enrollment
- 60 participants, estimated
- Lead sponsor
- Li Juntao
- Conditions
- Chronic Neck Pain
- Interventions
- Untangling Needle Therapy: Acupuncture with Untangling Needle, Sham acupuncture
- First posted
- 2026-10-23
- Last updated
- 2026-10-23
Source ClinicalTrials.gov
Registered outcomes5
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Visual Analogue Scale（VAS） | Baseline, immediately after treatment | * Score range: 0-10 points * 0 points: no pain * 10 points: the most severe pain imaginable * Meaning of the score: the higher the score, the more intense the pain (worse) |
| Primary | Trapezius shear modulus measured by a soft tissue mechanical imager using real-time shear wave elastography (SWE) technology and 2D ultrasound qualitative imaging features | Baseline, immediately after treatment | Using a soft tissue mechanical imaging device, we employ real-time shear wave elastography (SWE) to detect active myofascial trigger points (MTrPs) in the upper trapezius. Participants sit or lie face down, with their head and elbows fixed in position. The upper trapezius MTrPs are located using standardized palpation methods. The probe is coated with 4 mm of coupling gel and gently placed on the skin, avoiding the fascia layer in the measurement scale, with a 5 mm gap between the excitation handle and the probe marker. For each measurement point, 10 sets of data are collected, and values with a relative error of less than 10% are considered valid. The median of these valid values is taken as the shear modulus result. During the measurement process, 2D ultrasound images of the target area are also collected, and the assessor qualitatively records the 2D ultrasound features such as echoes and morphology. Higher shear modulus values indicate the upper trapezius tissue is stiffer. |
| Secondary | Cervical range of motion (ROM) | Baseline, immediately after treatment | Cervical spine mobility is assessed as active range of motion (A-ROM), including forward flexion, backward extension, side bending on both sides, and rotation on both sides. The higher the score (angle value), the greater the active movement range of the neck (which is better) |
| Secondary | Neck Disability Index (NDI-TH) | Baseline, immediately after treatment | The NDI-TH consists of 10 items, each worth 5 points, with a total score ranging from 0 (no disability) to 50 (complete paralysis). The higher the score, the more severe the functional impairment. |
| Secondary | Changes in oxygenated hemoglobin (HbO₂) concentration in the prefrontal and motor-related brain areas measured by multi-channel functional near-infrared spectroscopy (fNIRS) | Baseline, immediately after treatment | We used a multi-channel functional near-infrared spectroscopy (fNIRS) device with light source wavelengths set at 730 nm and 850 nm, and a sampling rate of 11 Hz. The device had 24 light sources and 16 detectors, giving a total of 48 measurement channels. The probes were placed according to the international 10-20 EEG system, with an average distance of 30 mm between light sources and detectors. The regions of interest included the left and right prefrontal cortex (PFC), left and right dorsolateral prefrontal cortex (DLPFC), premotor cortex / supplementary motor area (PMC/SMA), primary motor cortex (M1), and primary somatosensory cortex (S1). We preprocessed the raw data from the corresponding channels for each brain region and averaged the channels within each region to get the HbO₂ concentration for that area. Higher oxygenated hemoglobin values indicate higher local blood oxygen levels in that brain region. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07892495
GET https://conductscience.org/api/trials/v1/NCT07892495/registered