Trial · NCT07892742
The Effects of Increased Water Intake on Muscle Function, Physical Performance, and Endocrine Regulation in Low-Drinking Older Adults
NCT07892742, Not applicable, Recruiting, Polytechnic University of Santarém
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. The Effects of Increased Water Intake on Muscle Function, Physical Performance, and Endocrine Regulation in Low-Drinking Older Adults. Trials, record NCT07892742. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07892742
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- The Effects of Increased Water Intake on Muscle Function, Physical Performance, and Endocrine Regulation in Low-Drinking Older Adults
- NCT number
- NCT07892742
- Status
- Recruiting
- Phases
- Not applicable
- Enrollment
- 78 participants, estimated
- Lead sponsor
- Polytechnic University of Santarém
- Conditions
- Dehydrated, Water-Electrolyte Imbalance, Malnutrition, Dehydration (Physiology)
- Interventions
- Water
- First posted
- 2026-10-23
- Last updated
- 2026-11-12
Source ClinicalTrials.gov
Registered outcomes35
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Absolute and Relative Ankle Plantar-Flexion Peak Force | Day 1 (baseline) and Day 7 (post-intervention) | Absolute peak force (N) and relative peak force (N·kg-¹) during a seated maximal voluntary isometric plantar-flexion contraction of the dominant limb. The highest force value recorded across four trials will be used for analysis. |
| Primary | Rate of Force Development During Isometric Ankle Plantar-Flexion | Day 1 (baseline) and Day 7 (post-intervention) | Rate of force development (RFD; N·s-¹) during maximal voluntary isometric plantar-flexion of the dominant limb, calculated over consecutive 50-ms intervals from contraction onset: 0-50, 50-100, 100-150, and 150-200 ms. |
| Primary | Rate of Force Development During Dynamic Ankle Plantar-Flexion | Day 1 (baseline) and Day 7 (post-intervention) | Rate of force development (N·s-¹) during a standing bilateral rapid calf-raise task, calculated as peak force (N) divided by time to peak force (s). |
| Primary | Explosive Isometric Ankle Plantar-Flexion Force | Day 1 (baseline) and Day 7 (post-intervention) | Explosive force, expressed as the percentage of peak force (%F) attained at 50, 100, 150, and 200 ms following contraction onset during maximal voluntary isometric plantar-flexion of the dominant limb. |
| Primary | Peak Force during the 5 repetition STS | Day 1 (baseline) and Day 7 (post-intervention) | Peak vertical ground reaction force (N) recorded during the concentric phase of each sit-to-stand repetition. The participant-level summary measure will be defined a priori. |
| Primary | Fatigue Index During the 30-Second Sit-to-Stand Test | Day 1 (baseline) and Day 7 (post-intervention) | Fatigue index calculated to quantify the decline in performance across successive sit-to-stand repetitions during the 30-s STS. The calculation method will be specified a priori. |
| Primary | Mean Power During the 30-Second Sit-to-Stand Test | Day 1 (baseline) and Day 7 (post-intervention) | Mean lower-limb muscle power during the 30-s STS, estimated using a previously validated equation. |
| Secondary | Time to Complete the First Five Sit-to-Stand Repetitions | Day 1 (baseline) and Day 7 (post-intervention) | Time (s) required to complete the first five sit-to-stand repetitions during the 30-s STS test, measured from the onset of the first repetition until completion of the fifth repetition. Only participants completing at least five repetitions will be included in this analysis. |
| Secondary | Functional Lower-Limb Performance | Day 1 (baseline) and Day 7 (post-intervention) | Number of completed repetitions during the 30-second sit-to-stand test (30-s STS), performed from a 43-cm armless chair. |
| Secondary | Change in Handgrip strength | Day 1 (baseline) and Day 7 (post-intervention) | Handgrip strength will be assessed using a portable hand dynamometer (Jamar Plus+). Participants will perform three maximal voluntary isometric contractions with each hand alternately. A 60-second rest period will be provided between attempts. The highest recorded value will be used for analysis. The outcome will be expressed as the change in handgrip strength from baseline to the post-intervention assessment. |
1 to 10 of 35Source ClinicalTrials.gov
See all 35 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers21
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07892742
GET https://conductscience.org/api/trials/v1/NCT07892742/registered?page=2