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Trial · NCT07894510

Nanohydroxyapatite Versus Sodium Fluoride Varnish in Remineralizing MIH Anterior Teeth

NCT07894510, Not applicable, Recruiting, Tanta University

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Nanohydroxyapatite Versus Sodium Fluoride Varnish in Remineralizing MIH Anterior Teeth. Trials, record NCT07894510. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07894510

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Nanohydroxyapatite Versus Sodium Fluoride Varnish in Remineralizing MIH Anterior Teeth
NCT number
NCT07894510
Status
Recruiting
Phases
Not applicable
Enrollment
26 participants, estimated
Lead sponsor
Tanta University
Conditions
Fluoride Varnishes, Molar Incisor Hypomineralisation, Permanent Anterior Teeth, Remineralization
Interventions
Nanohydroxyapatite Varnish Application, Sodium Fluoride Varnish Application
First posted
2026-10-26
Last updated
2026-10-26

Source ClinicalTrials.gov

Registered outcomes2

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryQuantitative Enamel Remineralization / Laser Fluorescence (DIAGNOdent Score)Baseline (pre-application), 1 month, 3 months, and 6 months post-application.
Objective quantitative measurement of organic component breakdown and bacterial fluorescence within the enamel lesion using a calibrated DIAGNOdent device (KaVo Dental). Measured in peak numerical fluorescence units (0-99). A reduction in DIAGNOdent value relative to baseline indicates remineralization and structural mineral gain.
SecondaryVisual Caries Lesion Severity (ICDAS Score)Baseline (pre-application), 1 month, 3 months, and 6 months post-application.
Clinical visual assessment of non-cavitated MIH enamel lesions categorized according to the International Caries Detection and Assessment System (ICDAS) criteria following a 5-second air-drying step: Score 0: Sound tooth surface Score 1: First visual change in enamel (seen only after prolonged air drying) Score 2: Distinct visual change in enamel (visible when wet) Lower scores reflect lesion regression/remineralization; stable scores represent arrestment.

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers2

The papers the trial lists on ClinicalTrials.gov.

PMIDListed asSource
38457899RESULTPubMed
40744295RESULTPubMed

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT07894510

GET https://conductscience.org/api/trials/v1/NCT07894510/registered