Trial · NCT07895667
Adjunctive Diode Laser Therapy for Peri-Implant Mucositis
NCT07895667, Not applicable, Not yet recruiting, Universidad Europea de Valencia
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Adjunctive Diode Laser Therapy for Peri-Implant Mucositis. Trials, record NCT07895667. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07895667
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Adjunctive Diode Laser Therapy for Peri-Implant Mucositis
- NCT number
- NCT07895667
- Status
- Not yet recruiting
- Phases
- Not applicable
- Enrollment
- 144 participants, estimated
- Lead sponsor
- Universidad Europea de Valencia
- Conditions
- Peri-implant Mucositis
- Interventions
- Conventional Non-Surgical Treatment, FOX III Diode Laser Therapy
- First posted
- 2026-10-26
- Last updated
- 2026-10-26
Source ClinicalTrials.gov
Registered outcomes5
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change in Bleeding on Probing (BOP) | Baseline, 4-6 weeks, 3 months, 6 months, and 12 months | Bleeding on probing will be assessed at six sites per implant using the modified peri-implant index described by Mombelli. Probing will be performed with an approximate force of 0.25 N using a periodontal probe. Changes from baseline will be compared between the conventional non-surgical treatment group and the adjunctive diode laser group. |
| Secondary | Change in Probing Depth (PD) | Baseline, 4-6 weeks, 3 months, 6 months, and 12 months | Probing depth will be measured at six sites per implant and defined as the distance, in millimeters, between the peri-implant mucosal margin and the base of the peri-implant sulcus. Measurements will be performed with an approximate probing force of 0.25 N using a periodontal probe. |
| Secondary | Change in Plaque Index (PI) | Baseline, 4-6 weeks, 3 months, 6 months, and 12 months | Plaque index will be assessed at six sites per implant according to the criteria described by Silness and Löe. Changes from baseline will be evaluated during follow-up. |
| Secondary | Change in Peri-Implant Crevicular Fluid (PICF) Volume | Baseline and 4-6 weeks | Peri-implant crevicular fluid will be collected from the mesiobuccal region using Periopaper strips. PICF volume will be quantified using a Periotron 8010 and converted from arbitrary units to volume according to a previously established calibration curve. |
| Secondary | Change in Matrix Metalloproteinase-8 (MMP-8) Levels | Baseline and 4-6 weeks | Total MMP-8 concentration in peri-implant crevicular fluid will be determined using a commercially available human MMP-8 ELISA kit. Absorbance will be measured at 450 nm, and MMP-8 concentrations will be calculated by interpolation from the standard curve. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07895667
GET https://conductscience.org/api/trials/v1/NCT07895667/registered