Trial · NCT07895979
The Efficacy of an IADL-based Non-immersive Virtual Reality Training Program to Enhance ADL Performance and Cognitive Function for Persons at Risk of Dementia
NCT07895979, Not applicable, Recruiting, National Taiwan University Hospital
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. The Efficacy of an IADL-based Non-immersive Virtual Reality Training Program to Enhance ADL Performance and Cognitive Function for Persons at Risk of Dementia. Trials, record NCT07895979. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07895979
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- The Efficacy of an IADL-based Non-immersive Virtual Reality Training Program to Enhance ADL Performance and Cognitive Function for Persons at Risk of Dementia
- NCT number
- NCT07895979
- Status
- Recruiting
- Phases
- Not applicable
- Enrollment
- 216 participants, estimated
- Lead sponsor
- National Taiwan University Hospital
- Conditions
- Cognitive Enhancement, Subjective Cognitive Decline (SCD), Mild Cognitive Impairmen
- Interventions
- Daily Life VR Training, Non-Conditional Game VR Training, Traditional Cognitive Training
- First posted
- 2026-10-26
- Last updated
- 2026-11-09
Source ClinicalTrials.gov
Registered outcomes14
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Subjective Cognitive Decline Questionnaire (SCD-Q) | Baseline (within 2 weeks prior to intervention) and post-intervention (within 2 weeks after the 12-week intervention) | Assessed via a semi-structured interview based on the 24 items of the Subjective Cognitive Decline Questionnaire (SCD-Q). Participants identify up to 5 of their most concerning daily life cognitive difficulties and rate each item on two dimensions: (1) Frequency of occurrence, rated from 1 to 10 (where 10 indicates very frequent occurrence), and (2) Perceived distress/bother level, rated from 1 to 10 (where higher scores indicate lower distress, with 10 representing no distress at all). |
| Primary | The Brief University of California San Diego Performance-Based Skills Assessment-Traditional Chinese Version (UPSA-B) | Baseline (within 2 weeks prior to intervention) and post-intervention (within 2 weeks after the 12-week intervention) | An objective, performance-based measure that evaluates instrumental activities of daily living (IADL) in simulated real-world scenarios across two domains: financial skills and communication skills (telephone use). Total scores range from 0 to 100, with higher scores indicating better everyday functional performance. |
| Primary | IADL Context-Based Cognitive Flexibility Assessment (ICFA) | Baseline (within 2 weeks prior to intervention) and post-intervention (within 2 weeks after the 12-week intervention) | A performance-based assessment evaluating cognitive flexibility within daily life contexts across 5 IADL-related scenarios (e.g., public transportation use, financial management, and daily life problem-solving). Each scenario consists of two parts assessing (1) spontaneous cognitive flexibility and (2) reactive cognitive flexibility (including intra-dimensional and extra-dimensional shifting). Higher scores indicate better real-life cognitive flexibility. |
| Secondary | the Taiwanese Version of the Montreal Cognitive Assessment (MoCA-T) | Baseline (within 2 weeks prior to intervention) and post-intervention (within 2 weeks after the 12-week intervention) | Assesses global cognitive function across 8 cognitive domains: visuospatial/executive function, naming, memory, attention, language, abstraction, delayed recall, and orientation. Total scores range from 0 to 30, with higher scores indicating better global cognitive function. |
| Secondary | Color Trails Test (CTT) | Baseline (within 2 weeks prior to intervention) and post-intervention (within 2 weeks after the 12-week intervention) | Evaluates sustained attention, alternating attention, and executive function. Consists of two parts: CTT-1 requires connecting numbered circles from 1 to 25 in sequence as quickly as possible; CTT-2 requires connecting numbered circles from 1 to 25 while alternating between pink and yellow colors. Measured by completion time (in seconds), where shorter completion times indicate better attention and executive functioning. |
| Secondary | the Wechsler Memory Scale-Third Edition (WMS-III) Family Pictures Subtest | Baseline (within 2 weeks prior to intervention) and post-intervention (within 2 weeks after the 12-week intervention) | Evaluates immediate and delayed visual memory. Participants view 4 pictures of family scenes and are asked to recall the characters, their spatial locations, and their activities immediately and after a 25-to-35-minute delay. Scores for both immediate recall and delayed recall range from 0 to 64, with higher scores indicating better visual memory. |
| Secondary | the Wechsler Memory Scale-Third Edition (WMS-III) Spatial Span Subtest | Baseline (within 2 weeks prior to intervention) and post-intervention (within 2 weeks after the 12-week intervention) | Assesses visuospatial working memory. Participants tap blocks on a board in the same order (Spatial Span Forward) or reverse order (Spatial Span Backward) as demonstrated by the examiner. Scores for the forward and backward subscales each range from 0 to 16 (total score range: 0 to 32), with higher scores indicating better visuospatial working memory. |
| Secondary | Functional Magnetic Resonance Imaging (fMRI) | Baseline (within 2 weeks prior to intervention) and post-intervention (within 2 weeks after the 12-week intervention) | Evaluates changes in resting-state functional connectivity using a 3.0-Tesla MRI scanner (Magnetom Prisma, Siemens). Includes T1-weighted structural MRI (MPRAGE sequence) and blood-oxygen-level-dependent (BOLD) resting-state functional EPI sequences to assess neural network changes before and after the cognitive intervention. |
| Secondary | Word Sequence Learning Test | Baseline (within 2 weeks prior to intervention) and post-intervention (within 2 weeks after the 12-week intervention) | Assesses short-term and delayed verbal memory across learning and 10-minute delayed recall phases. Scoring includes position score (range: 0 to 60), accuracy score (range: 0 to 60), total learning score (range: 0 to 20), and 10-minute delayed recall score (range: 0 to 30). Higher scores in each component indicate better verbal learning and memory performance. |
| Secondary | Tower of Hanoi (TOH) Completion Time | Baseline (within 2 weeks prior to intervention) and post-intervention (within 2 weeks after the 12-week intervention) | A performance-based task evaluating executive planning and problem-solving skills. Participants move perforated disks of varying sizes across three pegs from an initial state to a goal state while adhering to specific rules. This outcome assesses task execution efficiency, measured as the total completion time in seconds across all test trials. Shorter completion times indicate better planning and problem-solving ability. |
1 to 10 of 14Source ClinicalTrials.gov
See all 14 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests1
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as |
|---|---|
| Tower of Hanoi | Secondary outcome |
Source ConductCognition
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07895979
GET https://conductscience.org/api/trials/v1/NCT07895979/registered