Trial · NCT07897058
Project E-Shift: A Harm Reduction Intervention for Chronically Unhoused Smokers.
NCT07897058, Not applicable, Completed, Thomas Jefferson University
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Project E-Shift: A Harm Reduction Intervention for Chronically Unhoused Smokers. Trials, record NCT07897058. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07897058
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Project E-Shift: A Harm Reduction Intervention for Chronically Unhoused Smokers.
- NCT number
- NCT07897058
- Status
- Completed
- Phases
- Not applicable
- Enrollment
- 44 participants, actual
- Lead sponsor
- Thomas Jefferson University
- Conditions
- Cigarette Smoking Behavior, E-Cigarette Use
- Interventions
- E-cigarette, Nicotine replacement therapy (patch, gum), both arms, CO-contingent financial incentives, both arms, Cessation counseling
- First posted
- 2026-10-27
- Last updated
- 2026-10-27
Source ClinicalTrials.gov
Registered outcomes9
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Number of Participants With Carbon Monoxide (CO)-Verified Combustible Cigarette Abstinence | 4, 8, and 12 weeks post-switch | Abstinence is defined as self-report of no combustible cigarette smoking in the past 7 days AND expired CO ≤6 parts per million (Vitalograph CO monitor). Reported by arm at each time point. Participants with missing data at a time point are counted as not abstinent (intention-to-treat). |
| Secondary | Expired Carbon Monoxide (CO) Level | Switch date (1 week post-baseline) and 1, 2, 3, 4, 8, 10, and 12 weeks post-switch | Mean expired CO in parts per million, measured by Vitalograph CO monitor. Lower values indicate less recent combustible smoke exposure. |
| Secondary | Number of Days Smoking Combustible Cigarettes in the Past 7 Days | 1, 2, 3, 4, 8, 10, 12, and 24 weeks post-switch | Self-reported number of days (range 0-7) on which the participant smoked combustible cigarettes in the past 7 days. Higher values indicate more smoking. |
| Secondary | Number of Participants by Past-7-Day Product Use Category | 1, 2, 3, 4, 8, 10, 12, and 24 weeks post-switch | Mutually exclusive categories derived from self-report: e-cigarette use only, combustible cigarette use only, dual use, and no use of either product. |
| Secondary | Number of Participants With Self-Reported 7-Day Point-Prevalence Combustible Cigarette Abstinence | 24 weeks post-switch | Self-report of no combustible cigarette smoking in the past 7 days. CO verification was not performed at this visit. |
| Secondary | Number of Participants Maintaining CO-Verified Abstinence After Incentive Discontinuation | 8, 10, and 12 weeks post-switch | Among participants with CO-verified combustible cigarette abstinence (self-report of no smoking in the past 7 days and expired CO ≤6 ppm) at week 4, the final incentivized visit, the number who remain CO-verified abstinent at unincentivized follow-up visits. |
| Secondary | Number of Randomized Participants Retained at 12 Weeks | 12 weeks post-switch | Number of randomized participants who completed the 12-week post-switch assessment. |
| Other | Withdrawal and Craving Symptoms as Measured by the Wisconsin Smoking Withdrawal Scale 2, Brief Version (WSWS2-B) | Baseline; switch date (1 week post-baseline); and 1, 2, 3, 4, 8, 10, and 12 weeks post-switch | The WSWS2-B is a 6-item self-report measure of nicotine withdrawal and craving symptoms in the past 24 hours (feeling upset, thinking about food, wanting to smoke, troubled sleep, feeling restless, trouble concentrating). Items are rated from 1 (not at all) to 7 (extremely), and the overall score is the mean of the 6 items. Range 1-7; higher scores indicate greater withdrawal and craving (worse outcome). At some visits, items 4-6 were administered on a 0-100 or 0-7 slider and were linearly rescaled to the 1-7 metric before scoring. |
| Other | Respiratory Symptoms as Measured by the American Thoracic Society Questionnaire (ATSQ) Total Score | Baseline; switch date (1 week post-baseline); and 1, 2, 3, 4, 8, 10, and 12 weeks post-switch | 8 self-report items assessing current frequency of respiratory symptoms (morning cough, cough throughout the day, wheezing, shortness of breath when walking, shortness of breath during exercise or stair climbing, phlegm with cough, chest pain or tightness, and getting very tired in a short time). Each item is rated from 1 (never) to 5 (every day), and the total score is the sum of the 8 items. Range 8-40; higher scores indicate more frequent respiratory symptoms (worse outcome). |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers17
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07897058
GET https://conductscience.org/api/trials/v1/NCT07897058/registered