Trial · NCT07897162
Effect of Smoking on Salivary and Serum Metabolomic Profiles in Periodontitis
NCT07897162, Completed, Ankara University
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Effect of Smoking on Salivary and Serum Metabolomic Profiles in Periodontitis. Trials, record NCT07897162. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07897162
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Effect of Smoking on Salivary and Serum Metabolomic Profiles in Periodontitis
- NCT number
- NCT07897162
- Status
- Completed
- Enrollment
- 48 participants, actual
- Lead sponsor
- Ankara University
- Conditions
- Periodontitis
- First posted
- 2026-10-27
- Last updated
- 2026-11-04
Source ClinicalTrials.gov
Registered outcomes6
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Relative Abundance of Salivary Metabolites | At the time of study enrollment (single time point) | Salivary metabolites will be analyzed using mass spectrometry-based untargeted metabolomic profiling. Relative metabolite abundances will be measured and compared among the four study groups according to periodontal and smoking status. |
| Primary | Relative Abundance of Serum Metabolites | At the time of study enrollment (single time point) | Serum metabolites will be analyzed using mass spectrometry-based untargeted metabolomic profiling. Relative metabolite abundances will be measured and compared among the four study groups according to periodontal and smoking status. |
| Secondary | Mean Probing Pocket Depth (PPD) | At the time of study enrollment (single time point) | Probing pocket depth (PPD) will be measured in millimeters (mm) using a periodontal probe. Mean PPD values will be calculated for each participant and compared among the four study groups. |
| Secondary | Mean Clinical Attachment Loss (CAL) | At the time of study enrollment (single time point) | Clinical attachment loss (CAL) will be measured in millimeters (mm) using a periodontal probe. Mean CAL values will be calculated for each participant and compared among the four study groups. |
| Secondary | Mean Full-Mouth Plaque Index (PI) | At the time of study enrollment (single time point) | Plaque Index (PI) will be assessed at six sites per tooth using a four-point scoring system (0-3): 0 = no plaque; 1 = thin plaque deposits; 2 = visible plaque accumulation in masses; and 3 = presence of dental calculus. The mean full-mouth PI score will be calculated by averaging the scores across all examined sites. Higher scores indicate greater plaque and/or calculus accumulation. |
| Secondary | Percentage of Sites with Bleeding on Probing (BOP) | At the time of study enrollment (single time point) | Bleeding on probing (BOP) will be assessed during periodontal examination and expressed as the percentage of bleeding sites relative to the total number of examined sites. BOP percentages will be compared among the four study groups. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07897162
GET https://conductscience.org/api/trials/v1/NCT07897162/registered