Effects of Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) on Cognition, Dual-Task Performance, and Interoceptive Accuracy
NCT07897175, Not applicable, Not yet recruiting, Toros University
Trial 10
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Effects of Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) on Cognition, Dual-Task Performance, and Interoceptive Accuracy | ClinicalTrials.gov |
| NCT number | NCT07897175 | ClinicalTrials.gov |
| Status | Not yet recruiting | ClinicalTrials.gov |
| Phases | Not applicable | ClinicalTrials.gov |
| Enrollment | 54 participants, estimated | ClinicalTrials.gov |
| Lead sponsor | Toros University | ClinicalTrials.gov |
| Conditions | Cognition, Healthy Volunteers | ClinicalTrials.gov |
| Interventions | Sham Stimulation, taVNS 30 Hz, taVNS 100 Hz | ClinicalTrials.gov |
| First posted | 2026-10-27 | ClinicalTrials.gov |
| Last updated | 2026-10-27 | ClinicalTrials.gov |
Registered outcomes 5
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Dual-Task Cost on 3-Meter Tandem Walk Test | Session 1 (Baseline, no stimulation) and Session 2 (1 week later, during taVNS or sham) | Dual-Task Cost (DTC, %) quantifies the decrement in tandem walking performance when simultaneously performing serial subtraction (counting backward by 3s from a 3-digit number). DTC (%) = \[(single-task time - dual-task time) / single-task time\] × 100. Higher DTC indicates greater cognitive-motor interference. | ClinicalTrials.gov |
| Primary | Stroop test | Session 1 (Baseline) and Session 2 (1 week later, during taVNS or sham) | Executive function assessed via Stroop Test (Stroop Anchor Form). The Stroop effect is the difference in response time and accuracy between the color-word incongruent and congruent conditions, reflecting inhibitory control capacity. | ClinicalTrials.gov |
| Primary | Simple and Choice Reaction Time - Deary-Liewald Task | Session 1 (Baseline) and Session 2 (1 week later, during taVNS or sham) | Processing speed assessed using the Deary-Liewald Reaction Time Task administered via psytoolkit.org. Two conditions: Simple Reaction Time (SRT: respond to single stimulus appearing on blue background) and Choice Reaction Time (CRT: respond to one of four stimuli with the corresponding key). Inter-stimulus interval randomized between 1-3 seconds. | ClinicalTrials.gov |
| Primary | Heartbeat Counting Task Score (Interoceptive Accuracy) | Session 1 (Baseline) and Session 2 (1 week later, during taVNS or sham) | Objective interoceptive accuracy assessed using the Schandry (1981) Heartbeat Counting Task. Participants silently count their own heartbeats during 25-, 35-, and 45-second intervals without external cues. Reported counts are compared with actual heart rate recorded via Polar H10 sensor. Accuracy score = 1 - \[Σ(\|reported - actual\| / actual)\] / 3. Scores range 0-1; higher scores indicate greater interoceptive accuracy. | ClinicalTrials.gov |
| Secondary | Resting Heart Rate Variability | Session 1 (Baseline) and Session 2 (1 week later, during taVNS or sham) | HRV assessed as an index of autonomic nervous system regulation using Polar H10 heart rate sensor (Polar Electro Oy, Kempele, Finland) synchronized via Bluetooth with the "ECG Analysis for Polar H10" smartphone application. Participants rest in a supported seated position for 1 minute after sensor calibration. Time-domain and frequency-domain HRV indices extracted. | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 0
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as | Source |
|---|
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 4
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|---|---|
| Arithmetic Fluency Task | Primary outcome | ConductCognition |
| Choice Reaction Time | Primary outcome | ConductCognition |
| Simple Reaction Time | Primary outcome | ConductCognition |
| Stroop Color-Word Test | Primary outcome | ConductCognition |
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)