Trial · NCT07897357
Trained vs. Untrained: Lower Extremity Pressure Changes
NCT07897357, Not applicable, Recruiting, University of Alberta
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Trained vs. Untrained: Lower Extremity Pressure Changes. Trials, record NCT07897357. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07897357
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Trained vs. Untrained: Lower Extremity Pressure Changes
- NCT number
- NCT07897357
- Status
- Recruiting
- Phases
- Not applicable
- Enrollment
- 200 participants, estimated
- Lead sponsor
- University of Alberta
- Conditions
- Trained Athletes, Untrained
- Interventions
- Lower body positive and negative pressure
- First posted
- 2026-10-27
- Last updated
- 2026-11-05
Source ClinicalTrials.gov
Registered outcomes5
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change in diffusing capacity for carbon monoxide (DLCO) | Days 2 and 3. Measurements will be taken during each stage of intervention (e.g., LBPP/LBNP), after a minimum of 2 minutes from the onset of each stage. | Diffusing capacity of carbon monoxide (DLCO) in selected exercise intensities, lower-body pressures, and body positions. DLCO is measured using the single-breath dual gas pulmonary diffusing capacity for nitric oxide and carbon monoxide technique. |
| Primary | Change in capillary blood volume (Vc) | Days 2 and 3. Measurements will be taken during each stage of intervention (e.g., LBPP/LBNP), after a minimum of 2 minutes from the onset of each stage. | Capillary blood volume is a component of DLCO and is measured with the single-breath dual gas pulmonary diffusing capacity for nitric oxide and carbon monoxide technique. |
| Primary | Change in membrane diffusing capacity (Dm) | Days 2 and 3. Measurements will be taken during each stage of intervention (e.g., LBPP/LBNP), after a minimum of 2 minutes from the onset of each stage. | Membrane diffusing capacity is a component of DLCO and is measured with the single-breath dual gas pulmonary diffusing capacity for nitric oxide and carbon monoxide technique. |
| Other | Cardiac structure and function | Day 4. Measurements will be taken during each stage of intervention (e.g., LBPP/LBNP), after a minimum of 2 minutes from the onset of each stage. | Echocardiography-derived right ventricular systolic pressure during exercise and lower-body pressure conditions. |
| Other | Change in peripheral venous pressure | Day 2. Measurements will be taken during each stage of intervention (e.g., LBPP/LBNP), after a minimum of 2 minutes from the onset of each stage. | Measured directly using the antecubital IV during lower body positive and negative pressure. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers4
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07897357
GET https://conductscience.org/api/trials/v1/NCT07897357/registered