Trial · NCT07897383
Investigating the Effects of 24 Hour LEAP2 Infusion in Individuals With Overweight and Obesity
NCT07897383, Phase 1, Phase 2, Not yet recruiting, University Hospital, Gentofte, Copenhagen
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Investigating the Effects of 24 Hour LEAP2 Infusion in Individuals With Overweight and Obesity. Trials, record NCT07897383. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07897383
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Investigating the Effects of 24 Hour LEAP2 Infusion in Individuals With Overweight and Obesity
- NCT number
- NCT07897383
- Status
- Not yet recruiting
- Phases
- Phase 1, Phase 2
- Enrollment
- 18 participants, estimated
- Lead sponsor
- University Hospital, Gentofte, Copenhagen
- Conditions
- Obesity & Overweight
- Interventions
- Liver-expressed antimicrobial peptide 2, Placebo
- First posted
- 2026-10-27
- Last updated
- 2026-10-27
Source ClinicalTrials.gov
Registered outcomes55
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Food intake | 24 hours | Difference in total energy intake during the standardized ad libitum meals. Energy intake will be quantified as kilojoules (kJ) during the 24 hours |
| Secondary | Total food intake/24 hours | 24 hours | kJ/kg body weight |
| Secondary | Total food intake/24 hours | 24 hours | Total food intakes, kcal/kg body weight |
| Secondary | Food intake lunch | 5 hours after infusion start | Food intake lunch in kJ |
| Secondary | Food intake dinner | 11 hours after infusion start | Food intake dinner in kJ |
| Secondary | Food intake breakfast | 23 hours after infusion start | Food intake breakfast in kJ |
| Secondary | Composite score of sensation of hunger | 24 hours | Composite score calculated as (hunger + prospective food intake + \[100 - fullness\] + \[100 - satiety\]) / 4 from 100 mm visual analog scales (0 = minimum, 100 = maximum sensation), reported as baseline-subtracted AUC excluding the nocturnal period. Unit: mm × min. |
| Secondary | Explicit liking (Leeds Food Preference Questionnaire) | 24 hours | Explicit liking for high-fat relative to low-fat foods. |
| Secondary | Postprandial plasma concentrations of glucose after liquid meal test | 45 mins to 5 hours | Postprandial plasma concentrations of glucose after liquid meal test (mmol/(L\*min)) |
| Secondary | Snack intake | 24 hours | Energy intake from the ad libitum snack buffet (kJ) |
1 to 10 of 55Source ClinicalTrials.gov
See all 55 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07897383
GET https://conductscience.org/api/trials/v1/NCT07897383/registered?page=2