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Trial · NCT07898046

Registered outcomes49

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryPerceived Lower-Extremity Muscle Soreness ScorePre-exercise, immediately post-exercise, and 6, 24, 48, and 72 hours after each HIIT session
Perceived lower-extremity muscle soreness was assessed using a 0-10 visual analogue scale (VAS), where 0 indicated no soreness and 10 indicated extreme soreness. The unit of measure was the VAS score (0-10). Assessments were performed at each specified time point following both HIIT sessions. This outcome is designated as the primary outcome for registry purposes in this retrospective registration; no single primary outcome was pre-specified in the original study protocol.
SecondarySerum Creatine Kinase ConcentrationPre-exercise, immediately post-exercise, and 6, 24, 48, and 72 hours after each HIIT sessionSerum creatine kinase (CK) concentration was measured as an indirect circulating marker associated with exercise-induced muscle damage. The unit of measure was U/L.
SecondarySerum Lactate Dehydrogenase ConcentrationPre-exercise, immediately post-exercise, and 6, 24, 48, and 72 hours after each HIIT sessionSerum lactate dehydrogenase (LDH) concentration was measured as an indirect circulating marker associated with exercise-related tissue and muscle stress. The unit of measure was U/L.
SecondarySerum Alanine Aminotransferase ConcentrationPre-exercise, immediately post-exercise, and 6, 24, 48, and 72 hours after each HIIT sessionSerum alanine aminotransferase (ALT) concentration was measured as a non-specific circulating aminotransferase associated with exercise-related tissue stress. The unit of measure was U/L.
SecondarySerum Aspartate Aminotransferase ConcentrationPre-exercise, immediately post-exercise, and 6, 24, 48, and 72 hours after each HIIT sessionSerum aspartate aminotransferase (AST) concentration was measured as a non-specific circulating aminotransferase associated with exercise-related tissue stress. The unit of measure was U/L.
SecondarySerum C-Reactive Protein ConcentrationPre-exercise, immediately post-exercise, and 6, 24, 48, and 72 hours after each HIIT sessionSerum C-reactive protein (CRP) concentration was measured as an inflammatory biomarker. The unit of measure was mg/L.
SecondarySerum Creatine Kinase-MB ConcentrationPre-exercise, immediately post-exercise, and 6, 24, 48, and 72 hours after each HIIT sessionSerum creatine kinase-MB (CK-MB) concentration was measured as an exploratory, non-specific index of exercise-related tissue stress. The unit of measure was ng/mL.
SecondarySerum Heart-Type Fatty Acid-Binding Protein ConcentrationPre-exercise, immediately post-exercise, and 6, 24, 48, and 72 hours after each HIIT sessionSerum heart-type fatty acid-binding protein (H-FABP) concentration was measured as an exploratory, non-specific index of exercise-related tissue stress. The unit of measure was ng/mL.
SecondaryCountermovement Jump HeightPre-exercise, immediately post-exercise, and 6, 24, 48, and 72 hours after each HIIT sessionCountermovement jump (CMJ) height was assessed as an indicator of lower-body neuromuscular performance and recovery. The unit of measure was cm.
SecondaryCountermovement Jump PowerPre-exercise, immediately post-exercise, and 6, 24, 48, and 72 hours after each HIIT sessionCountermovement jump (CMJ) power was assessed as an indicator of lower-body neuromuscular performance and recovery. The unit of measure was kW.
SecondaryCountermovement Jump Mean VelocityPre-exercise, immediately post-exercise, and 6, 24, 48, and 72 hours after each HIIT sessionCountermovement jump (CMJ) mean velocity was assessed as an indicator of lower-body neuromuscular performance and recovery. The unit of measure was m/s.
SecondaryCountermovement Jump Flight TimePre-exercise, immediately post-exercise, and 6, 24, 48, and 72 hours after each HIIT sessionCountermovement jump (CMJ) flight time was assessed as an indicator of lower-body neuromuscular performance and recovery. The unit of measure was ms.
SecondaryWhole-Blood Valine ConcentrationPre-exercise, immediately post-exercise, and 6, 24, 48, and 72 hours after each HIIT session
Whole-blood valine concentration was quantified using targeted liquid chromatography-tandem mass spectrometry (LC-MS/MS) from capillary blood collected by volumetric absorptive microsampling (VAMS). The unit of measure was µmol/L.
SecondaryWhole-Blood Phenylalanine ConcentrationPre-exercise, immediately post-exercise, and 6, 24, 48, and 72 hours after each HIIT sessionWhole-blood phenylalanine concentration was quantified using targeted LC-MS/MS from capillary blood collected by VAMS. The unit of measure was µmol/L.
SecondaryWhole-Blood Tyrosine ConcentrationPre-exercise, immediately post-exercise, and 6, 24, 48, and 72 hours after each HIIT sessionWhole-blood tyrosine concentration was quantified using targeted LC-MS/MS from capillary blood collected by VAMS. The unit of measure was µmol/L.
SecondaryWhole-Blood Tryptophan ConcentrationPre-exercise, immediately post-exercise, and 6, 24, 48, and 72 hours after each HIIT sessionWhole-blood tryptophan concentration was quantified using targeted LC-MS/MS from capillary blood collected by VAMS. The unit of measure was µmol/L.
SecondaryWhole-Blood Alanine ConcentrationPre-exercise, immediately post-exercise, and 6, 24, 48, and 72 hours after each HIIT sessionWhole-blood alanine concentration was quantified using targeted LC-MS/MS from capillary blood collected by VAMS. The unit of measure was µmol/L.
SecondaryWhole-Blood Beta-Alanine ConcentrationPre-exercise, immediately post-exercise, and 6, 24, 48, and 72 hours after each HIIT sessionWhole-blood beta-alanine concentration was quantified using targeted LC-MS/MS from capillary blood collected by VAMS. The unit of measure was µmol/L.
SecondaryWhole-Blood 2-Aminobutyric Acid ConcentrationPre-exercise, immediately post-exercise, and 6, 24, 48, and 72 hours after each HIIT sessionWhole-blood 2-aminobutyric acid concentration was quantified using targeted LC-MS/MS from capillary blood collected by VAMS. The unit of measure was µmol/L.
SecondaryWhole-Blood Gamma-Aminobutyric Acid ConcentrationPre-exercise, immediately post-exercise, and 6, 24, 48, and 72 hours after each HIIT sessionWhole-blood gamma-aminobutyric acid (GABA) concentration was quantified using targeted LC-MS/MS from capillary blood collected by VAMS. The unit of measure was µmol/L.

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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