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Trial · NCT07898163

Comparing Cross-Linked and Non-Cross-Linked Hyaluronic Acid for Early Healing After Tooth Extraction

NCT07898163, Not applicable, Completed, Cyprus Health and Social Sciences University

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Comparing Cross-Linked and Non-Cross-Linked Hyaluronic Acid for Early Healing After Tooth Extraction. Trials, record NCT07898163. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07898163

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Comparing Cross-Linked and Non-Cross-Linked Hyaluronic Acid for Early Healing After Tooth Extraction
NCT number
NCT07898163
Status
Completed
Phases
Not applicable
Enrollment
60 participants, actual
Lead sponsor
Cyprus Health and Social Sciences University
Conditions
Wound Healing After Tooth Extraction
Interventions
Cross-linked sodium hyaluronate 1%, Non-cross-linked low-molecular-weight hyaluronic acid, Gelatin sponge
First posted
2026-10-27
Last updated
2026-11-04

Source ClinicalTrials.gov

Registered outcomes5

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
Primaryercentage Reduction in Wound AreaPostoperative days 0, 3, 7, and 14
Wound area will be measured from standardized, calibrated clinical photographs using ImageJ. Percentage reduction will be calculated relative to baseline: \[(baseline wound area - follow-up wound area) / baseline wound area\] × 100. Results will be compared among the three groups over time.
SecondaryWound Healing Score (WHS)Postoperative days 3, 7, and 14Clinical wound healing will be assessed using the study's WHS, with a total score ranging from 0 to 9.
SecondaryIndex of Postoperative Recovery (IPR)Postoperative days 3, 7, and 14Postoperative recovery will be assessed using the IPR measure specified in the study protocol.
SecondaryPostoperative Pain IntensityPostoperative days 1, 3, and 7Pain intensity will be recorded using a 10-cm visual analogue scale (VAS), where 0 indicates no pain and 10 indicates the worst pain.
SecondaryPostoperative Analgesic ConsumptionPostoperative days 1-7The number of analgesic doses taken by each participant will be recorded in the postoperative medication log.

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers0

The papers the trial lists on ClinicalTrials.gov.

None in this release.

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT07898163

GET https://conductscience.org/api/trials/v1/NCT07898163/registered