Trial · NCT07898267
Gut Microbiota-Based Clinical Study of Akkermansia Supplementation for Overweight and Obesity
NCT07898267, Not applicable, Not yet recruiting, Second Affiliated Hospital of Nanchang University
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Gut Microbiota-Based Clinical Study of Akkermansia Supplementation for Overweight and Obesity. Trials, record NCT07898267. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07898267
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Gut Microbiota-Based Clinical Study of Akkermansia Supplementation for Overweight and Obesity
- NCT number
- NCT07898267
- Status
- Not yet recruiting
- Phases
- Not applicable
- Enrollment
- 150 participants, estimated
- Lead sponsor
- Second Affiliated Hospital of Nanchang University
- Conditions
- Obesity & Overweight
- Interventions
- Akkermansia Supplement, Placebo Supplement
- First posted
- 2026-10-27
- Last updated
- 2026-11-05
Source ClinicalTrials.gov
Registered outcomes28
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Percentage Change in Body Weight from Baseline at Week 12 | Baseline and Week 12 | Percentage change in body weight from baseline to Week 12, calculated as \[(body weight at Week 12 - body weight at baseline) / body weight at baseline\] × 100. The percentage change will be compared between the Akkermansia supplementation group and the placebo group. |
| Secondary | Change in Body Mass Index from Baseline | Baseline, Weeks 4, 8, 12, 18, and 24. | Change in body mass index (BMI), calculated as body weight in kilograms divided by height in meters squared, from baseline to each follow-up visit. Results will be reported in kg/m². |
| Secondary | Change in Waist Circumference from Baseline | Baseline, Weeks 4, 8, 12, 18, and 24. | Change in waist circumference from baseline at each follow-up visit. Waist circumference will be measured using the standardized study procedure and reported in centimeters. |
| Secondary | Change in Body Fat Percentage from Baseline | Baseline, Weeks 12 and 24. | Change in body fat percentage from baseline, measured using the body composition assessment method specified in the study protocol. Results will be reported as percentage points. |
| Secondary | Change in Fasting Blood Glucose from Baseline | Baseline, Weeks 12 and 24. | Change in fasting blood glucose concentration from baseline. Blood samples will be collected after the fasting period specified in the study protocol. Results will be reported in the laboratory's standard concentration unit. |
| Secondary | Change in Glycated Hemoglobin from Baseline | Baseline, Weeks 12 and 24. | Change in glycated hemoglobin (HbA1c) from baseline. Results will be reported as a percentage or in mmol/mol, according to the laboratory method. |
| Secondary | Change in Homeostatic Model Assessment of Insulin Resistance from Baseline | Baseline, Weeks 12 and 24. | Change in the homeostatic model assessment of insulin resistance (HOMA-IR) from baseline. HOMA-IR will be calculated using fasting glucose and fasting insulin according to the prespecified study method and reported as a dimensionless index. |
| Secondary | Change in Total Cholesterol from Baseline | Baseline, Weeks 12 and 24. | Change in serum total cholesterol concentration from baseline. Results will be reported in the laboratory's standard concentration unit. |
| Secondary | Change in Triglyceride Concentration from Baseline | Baseline, Weeks 12 and 24. | Change in serum triglyceride concentration from baseline. Results will be reported in the laboratory's standard concentration unit. |
| Secondary | Change in Low-Density Lipoprotein Cholesterol from Baseline | Baseline, Weeks 12 and 24. | Change in low-density lipoprotein cholesterol (LDL-C) concentration from baseline. Results will be reported in the laboratory's standard concentration unit. |
1 to 10 of 28Source ClinicalTrials.gov
See all 28 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07898267
GET https://conductscience.org/api/trials/v1/NCT07898267/registered?page=2