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Trial · NCT07898826

Functional Regulation of Autoreactive Lymphocytes: Phenotypic and Transcriptomic Investigations in Healthy Subjects

NCT07898826, Not applicable, Not yet recruiting, University Hospital, Brest

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Functional Regulation of Autoreactive Lymphocytes: Phenotypic and Transcriptomic Investigations in Healthy Subjects. Trials, record NCT07898826. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07898826

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Functional Regulation of Autoreactive Lymphocytes: Phenotypic and Transcriptomic Investigations in Healthy Subjects
NCT number
NCT07898826
Status
Not yet recruiting
Phases
Not applicable
Enrollment
300 participants, estimated
Lead sponsor
University Hospital, Brest
Conditions
Healthy Subjects
Interventions
Blood sampling at D0, Blood sampling at D0, M12 and M24
First posted
2026-10-27
Last updated
2026-10-27

Source ClinicalTrials.gov

Registered outcomes5

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryThe identification of auto-reactive cells in healthy subjects in response to the auto-antigens tested1 dayThis criterion will be assessed by the frequency of auto-reactive B lymphocytes identified (%).
SecondaryDetailed phenotyping of B-cell subpopulations1 day
SecondaryTranscriptomic results for a selected subset of the cohort (10%)1 day
SecondaryResults of functional analyses for a selected subset of the cohort (10%)1 Day
SecondaryEstablishment of a longitudinal biological sample collectionFrom 1 day to 24 monthsBiocollection comprising 300 patients after 3 years, 20% of whom will be followed up annually for 2 years

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers0

The papers the trial lists on ClinicalTrials.gov.

None in this release.

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT07898826

GET https://conductscience.org/api/trials/v1/NCT07898826/registered