Trial · NCT07899164
Efficacy of Propranolol in Traumatic Brain Injury Patients Admitted to the ICU: A Prospective, Randomized, Triple-Blind Study
NCT07899164, Phase 3, Recruiting, Fundació d'investigació Sanitària de les Illes Balears
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Efficacy of Propranolol in Traumatic Brain Injury Patients Admitted to the ICU: A Prospective, Randomized, Triple-Blind Study. Trials, record NCT07899164. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07899164
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Efficacy of Propranolol in Traumatic Brain Injury Patients Admitted to the ICU: A Prospective, Randomized, Triple-Blind Study
- NCT number
- NCT07899164
- Status
- Recruiting
- Phases
- Phase 3
- Enrollment
- 536 participants, estimated
- Lead sponsor
- Fundació d'investigació Sanitària de les Illes Balears
- Conditions
- Traumatic Brain Injury (TBI) Patients
- Interventions
- Propranolol + Placebo
- First posted
- 2026-10-27
- Last updated
- 2026-10-27
Source ClinicalTrials.gov
Registered outcomes3
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | In-hospital mortality | Through study completion | To compare in-hospital mortality in patients with traumatic brain injury (TBI) requiring ICU admission after receiving 14 days of treatment with propranolol versus placebo. |
| Secondary | Extended Glasgow Outcome Scale score | 1-month GOSE; 6-month GOSE | To compare the percentage of patients with traumatic brain injury (TBI) showing a good outcome (GOSE score ≥5) after receiving 14 days of treatment with propranolol versus placebo, at 1 month and 6 months post-injury. Glasgow Outcome Scale-Extended (GOSE) is a standardized 8-point clinical tool used to assess a patient's level of functional recovery and independence after a traumatic brain injury (TBI). From 1 (dead) to 8 (upper good recovery). |
| Secondary | Adverse events | 14-day treatment period | -Compare the occurrence of adverse effects between the two groups during the 14-day treatment period. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07899164
GET https://conductscience.org/api/trials/v1/NCT07899164/registered