Trial · NCT07899463
ESR1 Mutations in Metastatic Hormone Receptor-Positive Breast Cancer in the Greek Population
NCT07899463, Recruiting, Hellenic Cooperative Oncology Group
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. ESR1 Mutations in Metastatic Hormone Receptor-Positive Breast Cancer in the Greek Population. Trials, record NCT07899463. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07899463
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- ESR1 Mutations in Metastatic Hormone Receptor-Positive Breast Cancer in the Greek Population
- NCT number
- NCT07899463
- Status
- Recruiting
- Enrollment
- 500 participants, estimated
- Lead sponsor
- Hellenic Cooperative Oncology Group
- Conditions
- ESR1 Gene Mutation, Breast Cancer (Locally Advanced or Metastatic), Hormon Receptor Positive Breast Cancer
- First posted
- 2026-10-27
- Last updated
- 2026-10-27
Source ClinicalTrials.gov
Registered outcomes2
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Prevalence of ESR1 mutations | through study completion, an average of 1 year | The proportion of patients with metastatic HR+/HER2- breast cancer in Greece who have detectable ESR1 mutations, determined by next-generation sequencing (NGS) of circulating tumor DNA (liquid biopsy) among all patients tested. Data are collected retrospectively and prospectively from routine clinical visits. |
| Secondary | Association of ESR1 mutations with clinicopathological features | through study completion, an average of 1 year | Correlation of ESR1 mutation status with patient demographics, tumor subtype, prior therapies, disease progression, and other clinicopathological characteristics observed in routine clinical practice. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers9
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07899463
GET https://conductscience.org/api/trials/v1/NCT07899463/registered