Trial · NCT07899671
Registered outcomes12
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
1 to 12 of 12
Download this page as JSON| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Inter-trial coherence (ITC) to 1.8 Hz | At Visits 2 and 3 (up to approximately 4 weeks after Visit 1) | Inter-trial Coherence (ITC) is a measure of the strength of oscillatory phase-locking across trials. ITC values range from 1, reflecting completely phase-locked activity, to 0, indicating activity that is completely phase random with respect to the event of interest. |
| Primary | Word segmentation Score (triplet learning paradigm) | At Visits 2 and 3 (up to approximately 4 weeks after Visit 1) | Reaction Time Ratio: The difference in mean reaction time between the first and final syllable, divided by mean reaction time for the first syllable. |
| Primary | Word Learning Index (WLI) score (triplet learning paradigm) | At Visits 2 and 3 (up to approximately 4 weeks after Visit 1) | The ratio of Inter-Trial Coherence (ITC) of the delta range to Inter-trial Coherence (ITC) of the theta range. |
| Primary | Word Knowledge Accuracy (sentence learning paradigm) | At Visits 2 and 3 (up to approximately 4 weeks after Visit 1) | Accuracy: % correct, evaluated across 18 trials. |
| Primary | Sentence knowledge Accuracy (sentence learning paradigm) | At Visits 2 and 3 (up to approximately 4 weeks after Visit 1) | Accuracy: % correct, evaluated across 18 trials. |
| Primary | D Prime (Grammatical Discrimination) | At Visits 2 and 3 (up to approximately 4 weeks after Visit 1) | d prime (d'), evaluated across 18 trials. d'=0 indicates no distinction between the signal and noise. Hit rate matches false alarm rate. d'\>0: the higher the value, the stronger the distinction between signal and noise. d'\<0: the more negative, indicate that false alarm rate is greater than hit rate. |
| Secondary | Inter-trial coherence (ITC) to 5.4 Hz | At Visits 2 and 3 (up to approximately 4 weeks after Visit 1) | In electroencephalogram (EEG) analysis inter-trial coherence measures how consistently the phase of a specific brain wave frequency aligns across trials. (possible range is 0-1; 0 is no phase alignment; 1 is perfect phase alignment). The closer the ITC value to 1, the stronger the alignment. |
| Other | Language Standard Score | At Visit 1 (after enrollment) | Clinical Evaluation of Language Fundamentals - fifth edition (CELF-5). Standard score average is 100, Standard deviation is 15. Average range is 85-115. Higher scores reflect better performance on the test. |
| Other | Nonverbal IQ standard score | At Visit 1 (after enrollment) | Nonverbal IQ Index score (standard score) on the Kaufman brief intelligence test, second edition (K-BIT 2) to determine eligibility. Average score = 100, standard deviation (SD) = 15. Average range is 85-115. Higher scores reflect better performance on the test. |
| Other | Standard Score on rapid naming (Rapid Automatized Naming or RAN) test. | At Visit 1 (after enrollment) | Standard Score on rapid naming (Rapid Automatized Naming or RAN). Standard scores will be obtained (mean = 100, SD = 15). Average range is 85-115. Higher scores reflect better performance on the test. |
| Other | Standard Score on Letter Identification subtest - Woodcock Reading Mastery Test | At Visit 1 (after enrollment) | Standard Score on Letter Identification subtest - Woodcock Reading Mastery Test, Third Edition. Standard scores will be obtained (mean = 100, SD = 15). Average range is 85-115. Higher scores reflect better performance on the test. |
| Other | Standard score of phonological awareness, the Comprehensive Test of Phonological Processing, 2nd edition (CTOPP-2) | At Visit 1 (after enrollment) | Standard score of phonological awareness, the Comprehensive Test of Phonological Processing, 2nd edition (CTOPP-2). Standard scores will be obtained (mean = 100, SD = 15). Average range is 85-115. Higher scores reflect better performance on the test. |
Source ClinicalTrials.govtrials-2026-11-12-0.5.0
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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