Trial · NCT07899762
Nutrition and Swelling
NCT07899762, Phase 2, Not yet recruiting, University of California, San Francisco
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Nutrition and Swelling. Trials, record NCT07899762. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07899762
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Nutrition and Swelling
- NCT number
- NCT07899762
- Status
- Not yet recruiting
- Phases
- Phase 2
- Enrollment
- 80 participants, estimated
- Lead sponsor
- University of California, San Francisco
- Conditions
- Postoperative Recovery, Total Knee Arthroplasty
- Interventions
- Xcelerated Recovery Nutritional Supplement
- First posted
- 2026-10-28
- Last updated
- 2026-10-28
Source ClinicalTrials.gov
Registered outcomes13
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change in Mid-Patellar Circumference From Baseline | Baseline (preoperative), 2 weeks postoperative, and 1 month postoperative | Mid-patellar circumference of the operative knee will be measured in centimeters using a standardized measurement technique. Change from the preoperative baseline measurement will be compared between the Xcelerated Recovery nutritional supplement and control groups as a measure of postoperative tissue fluid balance. |
| Secondary | Change in Operative Knee Range of Motion From Baseline | Baseline (preoperative), 2 weeks postoperative, and 1 month postoperative | Operative knee flexion and extension will be measured in degrees. Measurements will be obtained using the same standardized approach at each study visit to evaluate change in knee mobility during postoperative recovery. |
| Secondary | Change in Timed Up and Go Test Time From Baseline | Baseline (preoperative), 2 weeks postoperative, and 1 month postoperative | Functional mobility will be assessed using the Timed Up and Go test. Participants will stand from a chair, walk to a designated point, turn, return to the chair, and sit down. Completion time will be recorded in seconds. |
| Secondary | Change in 10-Meter Walk Test Performance From Baseline | Baseline (preoperative), 2 weeks postoperative, and 1 month postoperative | Participants will complete the 10-meter walk test at the participant's usual walking pace. Walking performance will be assessed using the prespecified study metric. |
| Secondary | Change in Operative-Leg Quadriceps Strength From Baseline | Baseline (preoperative), 2 weeks postoperative, and 1 month postoperative | Quadriceps strength of the operative leg will be measured using a handheld dynamometer while the participant is seated with the knee flexed. Participants will push against the handheld device as strongly as comfortably possible. Strength will be recorded using the prespecified dynamometer measurement unit. |
| Secondary | Change in Pain Score From Baseline using the Visual Analog Scale (VAS) | Baseline (preoperative), 2 weeks postoperative, and 1 month postoperative | Participant-reported pain will be assessed using the Visual Analog Scale (VAS) ranging from 1 (no pain) to 10 (worse pain possible). Pain scores will be collected before surgery and at postoperative follow-up visits. |
| Secondary | Hospital Length of Stay in days following surgery until participant returns home | From surgical admission through hospital discharge, up to 6 weeks | Length of stay following total knee arthroplasty will be determined from the medical record and recorded as the time from hospital admission to discharge. |
| Secondary | All-Cause Hospital Readmission Within 30 Days | Within 30 days after surgery | The occurrence of hospital readmission following total knee arthroplasty will be determined through review of the medical record and recorded as the number and proportion of participants with at least one readmission. |
| Secondary | Postoperative Complications | From surgery through 1 month postoperative | Postoperative complications documented in the medical record will be collected and compared between study groups. |
| Secondary | Xcelerated Recovery Nutritional Supplement Adherence | From 7 days before surgery through 14 days after surgery | Participants assigned to the Xcelerated Recovery group will report the number of prescribed supplement doses missed during the supplementation period. Adherence will be summarized based on completed versus prescribed doses. |
1 to 10 of 13Source ClinicalTrials.gov
See all 13 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers3
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07899762
GET https://conductscience.org/api/trials/v1/NCT07899762/registered