Trial · NCT07900490
Recovery and Safety After Epidural Spinal Cord Stimulation in People With Spinal Cord Injury
NCT07900490, Active not recruiting, Hainan University
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Recovery and Safety After Epidural Spinal Cord Stimulation in People With Spinal Cord Injury. Trials, record NCT07900490. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07900490
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Recovery and Safety After Epidural Spinal Cord Stimulation in People With Spinal Cord Injury
- NCT number
- NCT07900490
- Status
- Active not recruiting
- Enrollment
- 6 participants, actual
- Lead sponsor
- Hainan University
- Conditions
- Spinal Cord Injury
- Interventions
- Epidural Spinal Cord Stimulation
- First posted
- 2026-10-28
- Last updated
- 2026-10-28
Source ClinicalTrials.gov
Registered outcomes10
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change in American Spinal Injury Association Impairment Scale (AIS) Grade | Pre-surgery and last available neurological follow-up, up to 24 months after implantation. | Change in American Spinal Injury Association Impairment Scale (AIS) grade from pre-surgery to the last available neurological follow-up, based on the International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI). AIS grades range from A (complete injury) to E (normal motor and sensory function in a person with previous deficits). Pre-surgery and follow-up grades and individual grade transitions will be described for each patient. |
| Primary | Number of Patients With Implantation-, Device-, or Stimulation-Related Adverse Events | From implantation to the last available safety follow-up, up to 24 months. | Number of patients with documented adverse events related to implantation, the stimulation system, or stimulation during follow-up. Events include infection, wound complications, electrode migration, hardware malfunction, and stimulation-related discomfort. Event type, severity, timing, and any treatment interruption or revision procedure will be summarized when documented. |
| Primary | Change in Medical Research Council (MRC) Muscle Strength Grades | From implantation to the last available safety follow-up, up to 24 months. | Changes in muscle strength from pre-surgery to the last available follow-up will be described using the Medical Research Council (MRC) scale. Each assessed muscle is graded from 0 (no contraction) to 5 (normal strength). Findings will be reported separately for each assessed muscle group and side. |
| Primary | Change in ISNCSCI Lower Extremity Motor Score | From implantation to the last available safety follow-up, up to 24 months. | Change in the lower extremity motor score of the International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI) from pre-surgery to the last available follow-up. The score is the sum of grades for five key muscle functions on each side and ranges from 0 to 50, with higher scores indicating better lower extremity motor function. |
| Primary | Change in ISNCSCI Light Touch Score | From implantation to the last available safety follow-up, up to 24 months. | Change in the light touch total score of the International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI) from pre-surgery to the last available follow-up. The bilateral total score ranges from 0 to 112, with higher scores indicating better light touch sensation. |
| Primary | Change in ISNCSCI Pin Prick Score | From implantation to the last available safety follow-up, up to 24 months. | Change in the pin prick total score of the International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI) from pre-surgery to the last available follow-up. The bilateral total score ranges from 0 to 112, with higher scores indicating better pin prick sensation. |
| Primary | Change in Neurogenic Bladder Symptom Score (NBSS) | From implantation to the last available safety follow-up, up to 24 months. | Change in the Neurogenic Bladder Symptom Score (NBSS) total score from pre-surgery to the last available follow-up. The total score ranges from 0 to 74, with higher scores indicating more severe bladder-related symptoms. Changes will be described for patients with available assessments. |
| Secondary | Change in Modified Ashworth Scale (MAS) Grades | From implantation to the last available safety follow-up, up to 24 months. | Changes in resistance to passive movement from pre-surgery to the last available follow-up will be described using the Modified Ashworth Scale (MAS). Grades are 0, 1, 1+, 2, 3, and 4, with higher grades indicating greater resistance to passive movement. Findings will be reported separately for each assessed muscle group and side. |
| Secondary | Change in Visual Analog Scale (VAS) Pain Score | From implantation to the last available safety follow-up, up to 24 months. | Change in pain intensity measured using the Visual Analog Scale (VAS) from pre-surgery to the last available follow-up. Scores range from 0 (no pain) to 10 (worst imaginable pain), with lower scores indicating less pain. |
| Secondary | Change in Barthel Index Score | From implantation to the last available safety follow-up, up to 24 months. | Change in the Barthel Index total score from pre-surgery to the last available follow-up. The score assesses independence in activities of daily living and ranges from 0 to 100, with higher scores indicating greater independence. Changes will be described for patients with available assessments. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07900490
GET https://conductscience.org/api/trials/v1/NCT07900490/registered