Trial · NCT07900685
A Comparison of Pulsed Field Ablation (PFA) vs Cryoablation for Atrial Fibrillation Under Deep Sedation
NCT07900685, Not applicable, Recruiting, East Sussex Healthcare NHS Trust
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. A Comparison of Pulsed Field Ablation (PFA) vs Cryoablation for Atrial Fibrillation Under Deep Sedation. Trials, record NCT07900685. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07900685
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- A Comparison of Pulsed Field Ablation (PFA) vs Cryoablation for Atrial Fibrillation Under Deep Sedation
- NCT number
- NCT07900685
- Status
- Recruiting
- Phases
- Not applicable
- Enrollment
- 60 participants, estimated
- Lead sponsor
- East Sussex Healthcare NHS Trust
- Conditions
- Atrial Fibrillation (AF)
- Interventions
- Catheter ablation, Deep sedation with midazolam and fentanyl or midazolam and remifentanil, Sedation with midazolam and fentanyl
- First posted
- 2026-10-28
- Last updated
- 2026-10-28
Source ClinicalTrials.gov
Registered outcomes4
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Percentage of patients able to complete protocol with pulsed field ablation without conversion to cryoablaton | 18 months | Target is 75% of patients |
| Secondary | Numeric Rating scale for pain - Pain severity index (PSI) | 18 months | 0-10 (high score = more pain) - comparison of pain scores between PFA and cryoablation |
| Secondary | - Patient Experience Questionnaire for post-procedural pain, discomfort - Visual Analogue Scale (VAS) - Atrial Fibrillation Specific Patient Reported Outcome Measures Questionnaire (AF-PROMs) questionnaire | 18 months | Patients mark with an X on a visual analogue scale how much pain/discomfort they experienced (0-10) - 10 being more pain; comparison of numerical scores between pulsed field ablation and cryoablation |
| Secondary | - Lab occupancy time/ skin-to-skin time | 18 months | Time in minutes |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07900685
GET https://conductscience.org/api/trials/v1/NCT07900685/registered