Trial · NCT07900737
Comparison of Two Timings of Levothyroxine Intake in Hypothyroid Patients: A Cross-over Randomized Control Trial
NCT07900737, Phase 4, Active not recruiting, Elyes Kamoun
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Comparison of Two Timings of Levothyroxine Intake in Hypothyroid Patients: A Cross-over Randomized Control Trial. Trials, record NCT07900737. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07900737
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Comparison of Two Timings of Levothyroxine Intake in Hypothyroid Patients: A Cross-over Randomized Control Trial
- NCT number
- NCT07900737
- Status
- Active not recruiting
- Phases
- Phase 4
- Enrollment
- 102 participants, estimated
- Lead sponsor
- Elyes Kamoun
- Conditions
- Hypothyroidism Primary
- Interventions
- Levothyroxine Pill, Levothyroxine Pill
- First posted
- 2026-10-28
- Last updated
- 2026-10-28
Source ClinicalTrials.gov
Registered outcomes2
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Stability of TSH levels with both timing of intake | From enrollment to 16 weeks after enrollment, with two TSH performed for each patient with a 8 weeks interval | The primary outcome is to compare TSH levels when levothyroxine is taken at fasting, and TSH levels (µUI/mL) when levothyroxine is taken three hours after breakfast. The investigators aim to confirm that TSH levels (µUI/mL)won't change despite the change of timing of intake, and TSH levels (µUI/mL) will be comparable in either group, i.e no significant difference of TSH levels (µUI/mL) regardless of the first arm of levothyroxin intake |
| Secondary | Girerd scale adherence and Likert satisfaction scale to change of timing of intake | from enrollment to 16 weeks after enrollment | The investigators aim to determine for each patient the adherence to each timing of intake, for a better statistical analysis and to assess wether the timing of intake affects the adherence. The adherence will be be determined using the Girerd scale, which is a six-item questionnaire from 0 to 6 points. A score of zero means a good adherence, a score of 1 or 2 means a moderate adherence, and a score of 3 and above means a poor adherence. The investigators will also determine the satisfaction using a Likert satisfaction scale ranging from 1 to 5, with 1 meaning very dissatisfied and 5 meaning very satisfied. This determination will be made after each timing to determine, at the end of the study, which timing was preferred by the enrolled patients |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07900737
GET https://conductscience.org/api/trials/v1/NCT07900737/registered