Trial · NCT07901270
Metabolic Changes in Heart Failure Patients Treated With Vericiguat
NCT07901270, Not yet recruiting, University of Salerno
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Metabolic Changes in Heart Failure Patients Treated With Vericiguat. Trials, record NCT07901270. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07901270
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Metabolic Changes in Heart Failure Patients Treated With Vericiguat
- NCT number
- NCT07901270
- Status
- Not yet recruiting
- Enrollment
- 30 participants, estimated
- Lead sponsor
- University of Salerno
- Conditions
- Heart Failure, Worsening Heart Failure, Heart Failure With Reduced Ejection Fraction
- Interventions
- Vericiguat
- First posted
- 2026-10-28
- Last updated
- 2026-10-29
Source ClinicalTrials.gov
Registered outcomes3
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Changes in Plasma Metabolomic and Lipidomic Profiles Following Vericiguat Initiation | Baseline, 3 months, and 6 months | Changes in the relative abundance of circulating metabolites and lipid species from baseline to 3 and 6 months after vericiguat initiation, assessed using untargeted liquid chromatography-mass spectrometry. Longitudinal changes will be analyzed to identify significantly altered molecular features and metabolic pathways associated with treatment exposure. |
| Secondary | Change in Left Ventricular Global Longitudinal Strain | Baseline, 3 months, and 6 months | Change in left ventricular ejection fraction (LVEF), expressed as a percentage and assessed by transthoracic echocardiography. |
| Secondary | Change in Left Ventricular Global Longitudinal Strain | Baseline, 3 months, and 6 months | Change in left ventricular global longitudinal strain (GLS), expressed as a percentage and measured by speckle-tracking echocardiography, to assess changes in left ventricular myocardial deformation. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers3
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07901270
GET https://conductscience.org/api/trials/v1/NCT07901270/registered