Trial · NCT07901374
Registered outcomes12
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
1 to 12 of 12
Download this page as JSON| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change in Knee Pain During Movement (Visual Analogue Scale) | Baseline, 1, 3, 6 and 12 months after the intervention | Pain during movement (walking or climbing stairs) in the index knee, measured on a 100 mm visual analogue scale and recorded in cm with one decimal (0 = no pain, 10 = worst imaginable pain). Higher scores indicate worse pain. |
| Secondary | Change in Knee Pain at Rest (Visual Analogue Scale) | Baseline, 1, 3, 6 and 12 months after the intervention | Pain at rest in the index knee, measured on a 100 mm visual analogue scale and recorded in cm with one decimal (0 = no pain, 10 = worst imaginable pain). Higher scores indicate worse pain. |
| Secondary | Change in Knee Function (WOMAC) | Baseline, 1, 3, 6 and 12 months after the intervention | Western Ontario and McMaster Universities Osteoarthritis Index (Likert 3.1). Total score 0-96 and subscales for pain (0-20), stiffness (0-8) and physical function (0-68). Higher scores indicate worse symptoms and function. |
| Secondary | Proportion of Participants Achieving the Minimal Clinically Important Difference in Pain | 1, 3, 6 and 12 months after the intervention | Percentage of participants with a reduction of at least 2 points from baseline in pain during movement (visual analogue scale, 0-10). |
| Secondary | Analgesic Consumption | Baseline, 1, 3, 6 and 12 months after the intervention | Number of days with analgesic use in the previous 4 weeks (0-28) and most potent analgesic used (none, paracetamol, NSAID, weak opioid, strong opioid). |
| Secondary | Number of Participants With Adverse Events | Up to 12 months after the intervention | Adverse events related to the diagnostic block, radiofrequency ablation or hyaluronic acid injection, systematically recorded at each visit. |
| Secondary | Retreatment or Rescue Treatment | Up to 12 months after the intervention | Proportion of participants requiring retreatment, rescue treatment (including corticosteroid injection) or indication of total knee arthroplasty, and time to first retreatment or rescue treatment. |
| Secondary | Health-Related Quality of Life (EQ-5D-5L) | Baseline, 6 and 12 months after the intervention | EQ-5D-5L descriptive system (5 dimensions, 5 levels; utility index calculated with the Spanish value set, where 1 = full health and higher values indicate better health) and EQ-VAS (0-100, higher scores indicate better health). |
| Secondary | Rate of Negative Diagnostic Genicular Nerve Blocks | 4 hours after the diagnostic block | Percentage of participants allocated to the radiofrequency arm with less than 50% pain reduction within 4 hours after the diagnostic block, who therefore do not receive radiofrequency ablation. |
| Secondary | Patient Global Assessment | Baseline, 1, 3, 6 and 12 months after the intervention | Patient global assessment of the impact of knee osteoarthritis, measured on a 100 mm visual analogue scale (0 = very well, 100 = very poor). Higher scores indicate worse status. |
| Secondary | Patient Global Impression of Change (PGIC) | 1, 3, 6 and 12 months after the intervention | Single 7-point item from "very much better" to "very much worse" compared with before the study treatment. Responders are participants reporting "much better" or "very much better". |
| Secondary | Proportion of OMERACT-OARSI Responders | 1, 3, 6 and 12 months after the intervention | Responder according to OMERACT-OARSI criteria, based on pain during movement, WOMAC physical function and patient global assessment, each expressed on a 0-100 scale: improvement in pain or function \>=50% and \>=20 points, or improvement \>=20% and \>=10 points in at least two of the three domains. |
Source ClinicalTrials.govtrials-2026-11-12-0.5.0
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this list from software.
Twenty rows a page, as JSON. No key.
GET https://conductscience.org/api/trials/v1/NCT07901374/registered