Trial · NCT07901517
Vacuum Compression Therapy and Tissue Oxygenation in Chronic Leg Ulcers
NCT07901517, Not applicable, Recruiting, BTL Industries Ltd.
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Vacuum Compression Therapy and Tissue Oxygenation in Chronic Leg Ulcers. Trials, record NCT07901517. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07901517
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Vacuum Compression Therapy and Tissue Oxygenation in Chronic Leg Ulcers
- NCT number
- NCT07901517
- Status
- Recruiting
- Phases
- Not applicable
- Enrollment
- 20 participants, estimated
- Lead sponsor
- BTL Industries Ltd.
- Conditions
- Leg Ulcers, Leg Ulcers Venous
- Interventions
- Vacuum Compression Therapy (VCT), Standard Wound Care
- First posted
- 2026-10-28
- Last updated
- 2026-10-28
Source ClinicalTrials.gov
Registered outcomes6
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change in Bilateral Foot Transcutaneous Oxygen Partial Pressure (TcPO2) | Baseline and Week 4 (post-treatment) | Measured in mmHg on the dorsum of the foot in both the ulcerated (treated) limb and the contralateral unaffected (untreated) limb in both study groups using transcutaneous oxygen monitoring. Higher values indicate improved local microvascular tissue oxygenation. |
| Primary | Change in Wound Surface Area Assessed by Digital Planimetry | Baseline and Week 4 (post-treatment) | Measured in square centimeters (cm2) using standardized clinical photographs analyzed with Fiji (ImageJ) software. Tracing of wound margins provides precise measurement of two-dimensional wound area reduction. A reduction in the measured surface area from baseline to Week 4 indicates clinical improvement and wound healing. |
| Secondary | Change in Regional (Calf) and Systemic (Subclavian) Transcutaneous Oxygen Partial Pressure (TcPO2) | Baseline and Week 4 (post-treatment) | Measured in mmHg at the calf region of the ulcerated (diseased) limb only and at the subclavian reference site across both study groups. These measurements evaluate regional periwound perfusion changes on the affected limb versus systemic baseline oxygenation. |
| Secondary | Change in Wound Length | Baseline and Week 4 (post-treatment) | The maximum linear dimension of the wound measured in centimeters (cm) using a standard single-use clinical ruler. |
| Secondary | Change in Wound Width | Baseline and Week 4 (post-treatment) | The maximum linear dimension perpendicular to the wound length, measured in centimeters (cm) using a standard single-use clinical ruler. |
| Secondary | Change in Wound Depth | Baseline and Week 4 (post-treatment) | The maximum vertical distance from the skin surface to the deepest point of the wound bed, measured in centimeters (cm) using a sterile probe/ruler. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07901517
GET https://conductscience.org/api/trials/v1/NCT07901517/registered