Trial · NCT07901777
Two-Year Weight Loss With GLP-1 Medications Compared With Sleeve Gastrectomy in Adults With Obesity
NCT07901777, Recruiting, Yuzuncu Yil University
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Two-Year Weight Loss With GLP-1 Medications Compared With Sleeve Gastrectomy in Adults With Obesity. Trials, record NCT07901777. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07901777
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Two-Year Weight Loss With GLP-1 Medications Compared With Sleeve Gastrectomy in Adults With Obesity
- NCT number
- NCT07901777
- Status
- Recruiting
- Enrollment
- 200 participants, estimated
- Lead sponsor
- Yuzuncu Yil University
- Conditions
- Obesity & Overweight
- Interventions
- GLP-1 Receptor Agonist Therapy, Laparoscopic Sleeve Gastrectomy
- First posted
- 2026-10-28
- Last updated
- 2026-11-06
Source ClinicalTrials.gov
Registered outcomes21
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Percentage of Total Body Weight change at 24 Months | 24 months after GLP-1 receptor agonist treatment initiation or sleeve gastrectomy. | Percentage of total body weight loss (%TWL), calculated as \[(baseline body weight - body weight at 24 months) / baseline body weight\] × 100. Baseline is the date of GLP-1 receptor agonist treatment initiation or sleeve gastrectomy. The outcome will be compared between the propensity score-matched treatment cohorts. |
| Secondary | Percentage of Total Body Weight change at Earlier Follow-Up Visits | At 1, 3, 6, and 12 months after treatment initiation. | Percentage of total body weight loss (%TWL), calculated as \[(baseline body weight - follow-up body weight) / baseline body weight\] × 100, compared between the treatment cohorts. |
| Secondary | Change in Body Weight | Baseline to months 1, 3, 6, 12, and 24. | Change in body weight from baseline, measured in kilograms, compared between the treatment cohorts. |
| Secondary | Change in Body Mass Index | Baseline to months 1, 3, 6, 12, and 24. | Change in body mass index (BMI) from baseline, calculated as body weight in kilograms divided by height in meters squared, compared between the treatment cohorts. |
| Secondary | Percentage of Participants Achieving at Least 5% Total Body Weight Loss | At months 1, 3, 6, 12, and 24. | Percentage of participants losing at least 5% of their baseline body weight, compared between the treatment cohorts. |
| Secondary | Percentage of Participants Achieving at Least 10% Total Body Weight Loss | At months 1, 3, 6, 12, and 24. | Percentage of participants losing at least 10% of their baseline body weight, compared between the treatment cohorts. |
| Secondary | Percentage of Participants Achieving at Least 15% Total Body Weight Loss | At months 1, 3, 6, 12, and 24. | Percentage of participants losing at least 15% of their baseline body weight, compared between the treatment cohorts. |
| Secondary | Percentage of Participants Achieving at Least 20% Total Body Weight Loss | At months 1, 3, 6, 12, and 24. | Percentage of participants losing at least 20% of their baseline body weight, compared between the treatment cohorts. |
| Secondary | Percentage of Participants Achieving at Least 25% Total Body Weight Loss | At months 1, 3, 6, 12, and 24. | Percentage of participants losing at least 25% of their baseline body weight, compared between the treatment cohorts. |
| Secondary | Percentage of Participants Experiencing Any Adverse Event During GLP-1 Therapy | From the first medication dose through 24 months. | Percentage of participants in the GLP-1 receptor agonist cohort experiencing at least one adverse event. Event type, onset, severity, and suspected relationship to medication will be recorded. |
1 to 10 of 21Source ClinicalTrials.gov
See all 21 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07901777
GET https://conductscience.org/api/trials/v1/NCT07901777/registered?page=2