Trial · NCT07901855
Effectiveness of Virtual Reality in Improving Upper Limb Function in Critically Ill Patients
NCT07901855, Not applicable, Recruiting, National and Kapodistrian University of Athens
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Effectiveness of Virtual Reality in Improving Upper Limb Function in Critically Ill Patients. Trials, record NCT07901855. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07901855
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Effectiveness of Virtual Reality in Improving Upper Limb Function in Critically Ill Patients
- NCT number
- NCT07901855
- Status
- Recruiting
- Phases
- Not applicable
- Enrollment
- 48 participants, estimated
- Lead sponsor
- National and Kapodistrian University of Athens
- Conditions
- Intensive Care Unit (ICU) Acquired Weakness (ICU - AW), Critical Illness
- Interventions
- Conventional Physiotherapy and Occupational Therapy, Fully Immersive Virtual Reality Training
- First posted
- 2026-10-28
- Last updated
- 2026-10-28
Source ClinicalTrials.gov
Registered outcomes15
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change in Eye-Hand Coordination Assessed Using the Rapid Assessment of Eye-Hand Coordination Test | Baseline (before the intervention) and Day 11 (after completion of the 10-day intervention programme). | Eye-hand coordination is assessed using finger-to-nose, finger-to-knee, and finger-chase tasks, with five trials per testing condition. Each upper limb is assessed separately.. Recorded measures include completion time in seconds, movement speed and coordination categories, reaching accuracy, and error type |
| Primary | Change in Fugl-Meyer Assessment of Upper Extremity Function (FMA-UE) scores. | Baseline and day 11 | Change from baseline to Day 11 in upper extremity motor function assessed using the Fugl-Meyer Assessment-Upper Extremity (FMA-UE) score. The assessment covers arm movements, wrist and hand function, coordination, sensation, passive joint motion, joint pain. Scores range from 0 to 126 points per assessed upper limb, with higher scores indicating better motor function. |
| Primary | Changes in Motor Assessment Scale Upper Limb (UL-MAS). Time frame: Baseline and day 11 | Baseline and day 11 | Upper limb motor function assessed using the three upper limb sections of the Motor Assessment Scale: upper arm function, hand movements, and advanced hand activities (items 6-8). Each section is scored from 0 to 6, giving a total score from 0 to 18 points per assessed upper limb. |
| Primary | Changes in Box and Block Test scores | Baseline (Before the intervention) and day 11 (After completion of the 10-day intervention) | The Box and Block Test assesses unilateral gross manual dexterity. Participants transfer blocks one at a time over a partition between two compartments of a box for 60 seconds. Multiple blocks carried at the same time count as a single block. Each hand is assessed seperately. The score is the number of blocks successfully transferred within the 60 sec, with a minimum of 0 blocks and a maximum of 150. Higher scores indicate better gross manual dexterity. Change is calculated, for each hand, as the difference of score between day 11 and baseline score. |
| Primary | Changes in Motor-FreeVisualPerceptionTEST-4 (MVPT-4) scores | Baseline (before the intervention) and day 11 (after completion of the 10-day programme) | The Motor-Free Visual Perception Test (MVPT-4) is a performance based measure comprised of 45 items presented on separated cards in one spiral bound book. The test assesses domains of visual discrimination, spatial relationships, visual memory, figure ground perception and visual closure. Answers are presented on a multiple choice format with no motor ability needed. Higher scores indicating better visuo-perceptual skills. Administration and scoring following the test manual. |
| Secondary | Changes in Suitability Evaluation Questionnaire (SEQ) | Day 11, after completion of the 10-day virtual reality intervention programme. | Participants in the virtual reality group complete the Suitability Evaluation Questionnaire (SEQ) after the intervention programme. Thirteen items are rated seperately from 1 to 5 and a 14th which is an open ended question. For items 1-11 scores answers range from 1 (not at all) to 5 (very much). Higher scores on 1-6 and 11 show greater enjoyment, presence, perceived performance, realism, clarity of instructions and perceived rehabilitation benefit. For items 7- 10 higher scores show greater discomfort, dizziness/nausea, eye discomfort and disorientation. For items 12 and 13 answers range from 1 (very easy) to 5 (very) difficult with higher scores indicating more difficulty of the application and device. Item 14 asks if participants felt comfortable during the vr sessions (yes/no) and if the answer is no, participants asked to explain the reasons. |
| Secondary | Changes in handgrip strength using the Jamar hydraulic hand dynamometer | Baseline and day 11 | Grip strength is recorded in kilograms (kg) for each tested hand. Higher values indicate greater grip strength |
| Secondary | Changes in Oxford Muscle Scale | Baseline and day 11 | Each tested muscle group is graded from 0 (no contraction) to 5 (normal muscle strength) |
| Secondary | Changes in Motricity Index Upper Extremity score | Baseline and day 11 | The assessment includes pinch grip, elbow flexion, and shoulder abduction. Each component is assigned a score from 0 to 33. The three component scores are summed and one point is added, giving a total score from 1 to 100 for each upper limb. |
| Secondary | Changes in Medical Research Council (MRC) Manual Muscle Testing Scale | Baseline and day 11 | Six muscle groups are tested bilaterally: shoulder abductors, elbow flexors, wrist extensors, hip flexors, knee extensors, and ankle dorsiflexors. Each is graded from 0 (no contraction) to 5 (normal muscle strength), giving a total score from 0 to 60 |
1 to 10 of 15Source ClinicalTrials.gov
See all 15 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07901855
GET https://conductscience.org/api/trials/v1/NCT07901855/registered