Trial · NCT07902011
CTEPH Differential Diagnosis Assisted by Enhanced Large Language Model Support
NCT07902011, Not applicable, Not yet recruiting, China-Japan Friendship Hospital
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. CTEPH Differential Diagnosis Assisted by Enhanced Large Language Model Support. Trials, record NCT07902011. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07902011
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- CTEPH Differential Diagnosis Assisted by Enhanced Large Language Model Support
- NCT number
- NCT07902011
- Status
- Not yet recruiting
- Phases
- Not applicable
- Enrollment
- 60 participants, estimated
- Lead sponsor
- China-Japan Friendship Hospital
- Conditions
- Chronic Thromboembolic Pulmonary Hypertension (CTEPH), Acute Pulmonary Embolism (PE), Pulmonary Artery Sarcoma
- Interventions
- Locked CTEPH-LLM Diagnostic Decision Support
- First posted
- 2026-10-28
- Last updated
- 2026-10-29
Source ClinicalTrials.gov
Registered outcomes7
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Stage 4 CTEPH Identification Sensitivity | At completion of Stage 4 for each case, within 14 days after the clinician's first formal case-reading session | The proportion of evaluable physician-case judgments for the 10 reference-standard CTEPH cases in which the physician's final Top-1 diagnosis after Stage 4 is CTEPH. The numerator is the number of correct CTEPH identifications and the denominator is the number of evaluable Stage 4 judgments for CTEPH cases. The between-group comparison will account for clustering by physician and case. |
| Primary | Stage 4 Three-Class Top-1 Diagnostic Accuracy | During the two formal case-reading sessions, completed within 14 days after the first session | The proportion of evaluable Stage 4 physician-case judgments in which the clinician's Top-1 diagnosis matches the reference diagnosis among CTEPH, acute PE, and PAS. |
| Secondary | Stage 4 Class-Specific Diagnostic Performance | During the two formal case-reading sessions, completed within 14 days after the first session | For CTEPH, acute PE, and PAS separately, sensitivity, specificity, positive predictive value, and negative predictive value will be calculated from evaluable Stage 4 Top-1 diagnoses against the prespecified reference standard. |
| Secondary | Diagnostic Response Time | During the two formal case-reading sessions, completed within 14 days after the first session | Total response time across all cases and response time at each information stage will be recorded automatically by the study platform. Time will be summarized in seconds or minutes, using means with standard deviations or medians with interquartile ranges as appropriate. |
| Secondary | Stage-Wise Diagnostic Change | During the two formal case-reading sessions, completed within 14 days after the first session | Changes in the clinician's Top-1 diagnosis and recorded diagnostic probabilities from Stage 1 through Stage 4 will be summarized, including the proportion of judgments that change between consecutive stages and between Stage 1 and Stage 4. |
| Secondary | AI-Assisted Correction Rate When the AI Recommendation Is Correct | During the two formal case-reading sessions, completed within 14 days after the first session | Among LLM-assisted judgments in which the clinician's diagnosis before considering the stage-specific AI output is incorrect and the AI Top-1 diagnosis is correct, the proportion in which the clinician submits the correct diagnosis after receiving the AI output. |
| Secondary | AI-Related Over-Reliance Rate When the AI Recommendation Is Incorrect | During the two formal case-reading sessions, completed within 14 days after the first session | Among LLM-assisted judgments in which the clinician's diagnosis before considering the stage-specific AI output is correct and the AI Top-1 diagnosis is incorrect, the proportion in which the clinician changes to the incorrect AI diagnosis after receiving the AI output. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07902011
GET https://conductscience.org/api/trials/v1/NCT07902011/registered