Trial · NCT07903454
Anterior Segment Anatomy Assessed by Swept-Source OCT in Ocular Surgery Patients
NCT07903454, Recruiting, Nanfang Hospital, Southern Medical University
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Anterior Segment Anatomy Assessed by Swept-Source OCT in Ocular Surgery Patients. Trials, record NCT07903454. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07903454
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Anterior Segment Anatomy Assessed by Swept-Source OCT in Ocular Surgery Patients
- NCT number
- NCT07903454
- Status
- Recruiting
- Enrollment
- 500 participants, estimated
- Lead sponsor
- Nanfang Hospital, Southern Medical University
- Conditions
- Cataract, Primary Angle-Closure Glaucoma
- Interventions
- Ocular anatomical parameters will be measured using a swept-source optical coherence tomography (SS-OCT) device (CASIA2; Tomey Corporation, Nagoya, Japan). The imaging examination will be used to asse
- First posted
- 2026-10-29
- Last updated
- 2026-10-29
Source ClinicalTrials.gov
Registered outcomes9
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change in Anterior Chamber Depth (ACD) | Preoperative baseline; postoperative day 1, week 1, month 1, and month 3 | Anterior chamber depth (ACD), defined as the distance from the posterior corneal surface to the anterior lens surface along the visual axis, will be measured in millimeters (mm) using swept-source anterior segment optical coherence tomography (SS-OCT; CASIA2). Changes from the preoperative baseline will be calculated at each postoperative follow-up visit. |
| Primary | Change in Anterior Chamber Width (ACW) | Preoperative baseline; postoperative day 1, week 1, month 1, and month 3 | Anterior chamber width (ACW), defined as the distance between the nasal and temporal scleral spurs, will be measured in millimeters (mm) using swept-source anterior segment optical coherence tomography (SS-OCT; CASIA2). Changes from the preoperative baseline will be calculated at each postoperative follow-up visit. |
| Primary | Change in Anterior Chamber Volume (ACV) | Preoperative baseline; postoperative day 1, week 1, month 1, and month 3 | Anterior chamber volume (ACV) will be quantified in cubic millimeters (mm³) using the anterior chamber analysis function of swept-source anterior segment optical coherence tomography (SS-OCT; CASIA2). Changes from the preoperative baseline will be calculated at each postoperative follow-up visit. |
| Primary | Change in Angle Opening Distance at 500 μm (AOD500) | Preoperative baseline; postoperative day 1, week 1, month 1, and month 3 | Angle opening distance at 500 μm (AOD500) will be measured in millimeters (mm) using swept-source anterior segment optical coherence tomography (SS-OCT; CASIA2). AOD500 is defined as the distance between the corneal endothelium and the anterior iris surface along a line perpendicular to the trabecular meshwork at 500 μm from the scleral spur. Changes from the preoperative baseline will be calculated at each postoperative follow-up visit. |
| Primary | Change in Trabecular-Iris Space Area at 500 μm (TISA500) | Preoperative baseline; postoperative day 1, week 1, month 1, and month 3 | Trabecular-iris space area at 500 μm (TISA500) will be measured in square millimeters (mm²) using swept-source anterior segment optical coherence tomography (SS-OCT; CASIA2). TISA500 represents the cross-sectional area of the anterior chamber angle bounded by the trabecular meshwork, anterior iris surface, and reference lines at the scleral spur and 500 μm from the scleral spur. Changes from the preoperative baseline will be calculated at each postoperative follow-up visit. |
| Primary | Change in Trabecular-Iris Angle at 500 μm (TIA500) | Preoperative baseline; postoperative day 1, week 1, month 1, and month 3 | Trabecular-iris angle at 500 μm (TIA500) will be measured in degrees using swept-source anterior segment optical coherence tomography (SS-OCT; CASIA2). The angle will be determined from the anterior chamber angle geometry at 500 μm from the scleral spur. Changes from the preoperative baseline will be calculated at each postoperative follow-up visit. |
| Primary | Change in Iris Curvature (IC) | Preoperative baseline; postoperative day 1, week 1, month 1, and month 3 | Iris curvature (IC) will be quantified in millimeters (mm) using swept-source anterior segment optical coherence tomography (SS-OCT; CASIA2). Iris curvature is defined as the maximum perpendicular distance between the posterior iris surface and a reference line connecting the iris root to the pupillary margin. Changes from the preoperative baseline will be calculated at each postoperative follow-up visit. |
| Secondary | Correlation Between Preoperative Ocular Biometric Parameters and Postoperative Visual Acuity | Preoperative baseline; postoperative day 1, week 1, month 1, and month 3 | Preoperative ocular biometric parameters, including axial length (AL, mm), anterior chamber depth (ACD, mm), lens thickness (LT, mm), and white-to-white distance (WTW, mm), will be measured using swept-source anterior segment optical coherence tomography (SS-OCT; CASIA2). Postoperative visual acuity will be assessed using a standardized visual acuity chart and expressed in logarithm of the minimum angle of resolution (logMAR) units. Correlations between each preoperative biometric parameter and postoperative visual acuity will be evaluated using Pearson's or Spearman's correlation coefficient, as appropriate. Correlation coefficients will be reported as dimensionless values ranging from -1 to +1 |
| Secondary | Correlation Between Preoperative Ocular Biometric Parameters and Postoperative Spherical Equivalent Refraction | Preoperative baseline; postoperative day 1, week 1, month 1, and month 3 | Preoperative ocular biometric parameters, including axial length (AL, mm), anterior chamber depth (ACD, mm), lens thickness (LT, mm), and white-to-white distance (WTW, mm), will be measured using swept-source anterior segment optical coherence tomography (SS-OCT; CASIA2). Postoperative refractive status will be assessed by refraction examination and expressed as spherical equivalent refraction (SER) in diopters (D), calculated as spherical power plus half of the cylindrical power. Correlations between each preoperative biometric parameter and postoperative SER will be evaluated using Pearson's or Spearman's correlation coefficient, as appropriate. Correlation coefficients will be reported as dimensionless values ranging from -1 to +1. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07903454
GET https://conductscience.org/api/trials/v1/NCT07903454/registered