Trial · NCT07903675
Effectiveness of the Autism Pupil Screen (APS) Detect Pupillometer for Identifying Autism Spectrum Disorder (ASD) in Routine Healthcare
NCT07903675, Recruiting, Schweitzer Engineering Laboratories
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Effectiveness of the Autism Pupil Screen (APS) Detect Pupillometer for Identifying Autism Spectrum Disorder (ASD) in Routine Healthcare. Trials, record NCT07903675. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07903675
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Effectiveness of the Autism Pupil Screen (APS) Detect Pupillometer for Identifying Autism Spectrum Disorder (ASD) in Routine Healthcare
- NCT number
- NCT07903675
- Status
- Recruiting
- Enrollment
- 330 participants, estimated
- Lead sponsor
- Schweitzer Engineering Laboratories
- Conditions
- Autism Spectrum Disorder
- Interventions
Autism Pupil Screen (APS) Detect PLR Assessment #1, Modified Checklist for Autism in Toddlers, Revised with Follow-up (M-CHAT/R-F), Social Responsiveness Scale, Second Edition (SRS-2), Autism Diagnostic Observation Schedule, Second Edition (ADOS-2), Mullen Scales of Early Learning (MSEL), Adaptive Behavior Assessment System, Third Edition (ABAS-3), Autism Pupil Screen (APS) Detect PLR Assessment #2, Autism Pupil Screen (APS) Detect Assessment #3, Well-child check
- First posted
- 2026-10-29
- Last updated
- 2026-10-29
Source ClinicalTrials.gov
Registered outcomes3
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Sensitivity and Specificity of the APS Score to classify ASD diagnostic outcome | From enrollment to the end of all testing visits will be 14-30 days | This study will test the effectiveness of the APS Detect device results to accurately identify an atypical PLR score for children meeting the criteria for ASD. The study will also test the effectiveness of the APS Detect device results to accurately identify a typical PLR score for children who do not have ASD and have been identified as typically developing. |
| Secondary | Positive Predictive Values and Negative Predictive Values | From enrollment to the end of all testing visits will be 14-30 days | These measures will assess the ability of the APS Detect score to predict the diagnostic outcome taking into consideration the prevalence of ASD, using prevalence rates reported by the Autism and Developmental Disabilities Monitoring Network. This measure will be taken at the end of the study for all child study participants enrolled. This helps determine how likely the device is to detect ASD in routine screening when compared to the general population. |
| Other | Precision Study: Reliability and Reproducibility of the results of the APS Detect | From enrollment to the end of all testing visits will be 14-30 days | Study participants selected for Arm B of this trial will be tested to evaluate how consistent the results are for the APS Detect. This part of the study will assess the percent of agreement between outcome measures obtained with the APS Detect over more than one administration of the pupil screening test administered by a different clinician for each test administration. A test of each individual pupil measurement that contributes to the APS Score will analyze the influence of those measurements on the final result obtained across study participants. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers7
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07903675
GET https://conductscience.org/api/trials/v1/NCT07903675/registered