Trial · NCT07904741
The Effect of Different Exercise Training Programs on Muscle Oxygenation in Individuals With Knee Osteoarthritis
NCT07904741, Not applicable, Recruiting, Bahçeşehir University
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. The Effect of Different Exercise Training Programs on Muscle Oxygenation in Individuals With Knee Osteoarthritis. Trials, record NCT07904741. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07904741
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- The Effect of Different Exercise Training Programs on Muscle Oxygenation in Individuals With Knee Osteoarthritis
- NCT number
- NCT07904741
- Status
- Recruiting
- Phases
- Not applicable
- Enrollment
- 60 participants, estimated
- Lead sponsor
- Bahçeşehir University
- Conditions
- Osteoarthritis of Knee
- Interventions
- Recumbent-Cycle Aerobic Exercise, Lower-Limb Strengthening Exercise, Home Flexibility Exercise Program
- First posted
- 2026-10-29
- Last updated
- 2026-10-29
Source ClinicalTrials.gov
Registered outcomes8
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Muscle Oxygenation | Baseline, week 3, week 6, week 10 | 1. Resting VMO Muscle Oxygen Saturation (SmO₂): Mean muscle oxygen saturation (SmO₂, %) recorded over 60 seconds after 10 minutes of seated rest, measured over the vastus medialis oblique using near-infrared spectroscopy. 2. Minimum VMO SmO₂ During Mini-Squat Exercise: Minimum muscle oxygen saturation (SmO₂, %) recorded over the vastus medialis oblique during one set of 20 mini-squats performed at approximately 30 degrees of knee flexion, with a 3- to 4-second hold per repetition and isometric hip adduction. 3. Post-Exercise VMO SmO₂ Recovery Time: Time in seconds from completion of the mini-squat set until SmO₂ returns to the pre-exercise resting baseline, measured over the vastus medialis oblique. |
| Secondary | Knee Pain | Baseline, week 3, week 6, week 10 | Participant-rated knee pain at rest using a 0-to-10 Numerical Rating Scale (NRS), where 0 indicates no pain and 10 indicates the worst pain imaginable. |
| Secondary | WOMAC Score | Baseline, week 3, week 6, week 10 | The Turkish version of the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) will assess pain, stiffness, and physical function. The total score will be normalized to a 0-to-100 scale using (raw total score × 100) / 96; higher scores indicate worse symptoms and function. |
| Secondary | SF-36 Health-Related Quality of Life | Baseline, week 3, week 6, week 10 | The Turkish version of the 36-Item Short Form Health Survey (SF-36) will be scored across its eight domains on a 0-to-100 scale. Higher scores indicate better health-related quality of life. |
| Secondary | Active Knee Flexion Range of Motion | Baseline, week 3, week 6, week 10 | Active knee flexion range of motion, measured in degrees with a universal goniometer. Three measurements will be taken and the mean will be used. |
| Secondary | Maximal Isometric Knee Extension Torque | Baseline and weeks 3, 6, and 10. | Maximal isometric knee extension torque, measured in Newton-meters using an isokinetic dynamometer at 15 degrees of knee flexion. Three contractions will be performed and the mean torque will be used. |
| Secondary | 30-Second Sit-to-Stand Test | Baseline and weeks 3, 6, and 10. | Number of complete sit-to-stand repetitions performed in 30 seconds from a chair with a seat height of 44 cm, with arms crossed over the chest. |
| Secondary | 2-Minute Walk Test | Baseline and weeks 3, 6, and 10. | Distance walked in meters during a 2-minute walk test on a 30-meter corridor. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07904741
GET https://conductscience.org/api/trials/v1/NCT07904741/registered