Trial · NCT07904936
Fresh Versus Vitrified-Warmed Donor Oocytes: Embryological and Clinical Outcomes
NCT07904936, Active not recruiting, Center for Reproductive Medicine Bocian
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Fresh Versus Vitrified-Warmed Donor Oocytes: Embryological and Clinical Outcomes. Trials, record NCT07904936. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07904936
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Fresh Versus Vitrified-Warmed Donor Oocytes: Embryological and Clinical Outcomes
- NCT number
- NCT07904936
- Status
- Active not recruiting
- Enrollment
- 3,000 participants, estimated
- Lead sponsor
- Center for Reproductive Medicine Bocian
- Conditions
- Infertility, Donor Oocyte Assisted Reproduction
- Interventions
- Fresh Donor Oocyte ICSI, Vitrified-Warmed Donor Oocyte ICSI
- First posted
- 2026-10-29
- Last updated
- 2026-10-29
Source ClinicalTrials.gov
Registered outcomes7
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Live Birth Following the First Embryo Transfer per Initial Donor-Oocyte Allocation | From initial donor-oocyte allocation through the pregnancy outcome of the first embryo transfer, assessed up to December 2027. | Proportion of eligible recipient allocations resulting in at least one live-born infant following the first embryo transfer derived from the initial donor-oocyte allocation. The denominator includes all eligible allocations of six mature (MII) donor oocytes, including those resulting in no transferable embryo or no embryo transfer. Each allocation contributes a maximum of one successful outcome. Allocations without a first transfer or with unresolved birth outcomes at the data cutoff will be identified and handled according to the prespecified analysis plan. |
| Secondary | Mature Oocyte Availability for ICSI per Initial Allocation | From initial allocation to ICSI (Day 0). | Number of mature donor oocytes available for ICSI relative to the initial allocation of six MII oocytes. The measure captures quantitative loss before insemination and is compared between fresh and vitrified-warmed cohorts. |
| Secondary | Normal Fertilization Rate | Approximately 16-20 hours after ICSI (Day 1). | Proportion of injected MII oocytes exhibiting normal fertilization (2PN). Calculated per oocyte injected by ICSI, with the number of 2PN embryos per initial allocation also assessed. |
| Secondary | Usable Blastocyst Yield per Initial Oocyte Allocation | Within 5-7 days after ICSI. | Number of usable blastocysts obtained from the initial donor-oocyte allocation, including allocations producing zero usable blastocysts. Usability is determined according to the participating laboratory's clinical criteria for transfer or cryopreservation. |
| Secondary | Availability of at Least One Usable Blastocyst | Within 5-7 days after ICSI. | Proportion of initial donor-oocyte allocations producing at least one usable blastocyst suitable for embryo transfer or cryopreservation. All eligible allocations remain in the denominator. |
| Secondary | First Embryo Transfer Opportunity | From initial allocation through December 2027. | Proportion of eligible initial donor-oocyte allocations resulting in at least one embryo transfer derived from the allocated oocytes within the prespecified follow-up period. Allocations without a transfer are retained in the denominator. |
| Secondary | Cumulative Live Birth per Initial Oocyte Allocation | From initial allocation through June 2028. | Proportion of eligible initial donor-oocyte allocations resulting in at least one live birth from any embryo transfer derived from that allocation within the prespecified follow-up period. Assessed in a cohort with sufficiently complete follow-up; allocations with unresolved outcomes will be identified and addressed in the analysis. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07904936
GET https://conductscience.org/api/trials/v1/NCT07904936/registered