Trial · NCT07905079
Retrospective Study of Corneal Tissue Addition Keratoplasty for Keratoconus and Post-Refractive Ectasia
NCT07905079, Completed, Corneagen LLC
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Retrospective Study of Corneal Tissue Addition Keratoplasty for Keratoconus and Post-Refractive Ectasia. Trials, record NCT07905079. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07905079
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Retrospective Study of Corneal Tissue Addition Keratoplasty for Keratoconus and Post-Refractive Ectasia
- NCT number
- NCT07905079
- Status
- Completed
- Enrollment
- 61 participants, actual
- Lead sponsor
- Corneagen LLC
- Conditions
- Keratoconus; Post-Refractive Ectasia
- Interventions
- Corneal Tissue Addition Keratoplasty (CTAK)
- First posted
- 2026-10-29
- Last updated
- 2026-10-29
Source ClinicalTrials.gov
Registered outcomes9
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change in K2 (Steep Keratometry) | Baseline to 6 months | Change in steep corneal keratometry, measured in diopters, from preoperative baseline to six months after CTAK. |
| Primary | Change in Maximum Keratometry (Kmax) from preoperative baseline to six months after CTAK | Baseline to 6 months | Maximum corneal keratometry is measured in diopters using corneal tomography. |
| Primary | Change in Mean Keratometry (Kmean) from preoperative baseline to six months after CTAK | Baseline to 6 months | Mean corneal keratometry is measured in diopters using corneal tomography. |
| Secondary | Change in Uncorrected Distance Visual Acuity (UDVA) from baseline to 6 months | Baseline to 6 months | Measured using the site's Standard of Care practice for collecting visual acuity and recorded in Snellen notation. |
| Secondary | Change in Corrected Distance Visual Acuity (CDVA) from baseline to 6 months | Baseline to 6 months | Measured using the site's Standard of Care practice for collecting visual acuity and recorded in Snellen notation. |
| Secondary | Refractive Stability | Baseline through available follow-up | Change in post-operative MRSE and astigmatism from baseline to 6-months, when available. |
| Secondary | Number of Participants with CTAK-Related Adverse Events and Complications as Assessed by Protocol v2.0 | From CTAK surgery through 6-months post-op | Incidence of documented clinically significant procedure-related complications and secondary surgical interventions. |
| Secondary | Progression to Corneal Transplantation | From CTAK surgery through 6-months post-op | Number and Proportion of Study Eyes that Progressed to Undergoing a Corneal Transplant following CTAK. |
| Secondary | Comparison of Change in Keratometry Measurements from Baseline to 6-months by Primary Payer Category | Baseline to 6 months | Exploratory comparison of changes in Maximum Keratometry (Kmax), Mean Keratometry (Kmean), and Steep Keratometry (K2) from baseline to the 6-month postoperative visit across payer categories. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07905079
GET https://conductscience.org/api/trials/v1/NCT07905079/registered