Trial · NCT07905105
A Study of CYT-1010 in Healthy Volunteers and Participants With Acute Pain After Third Molar Extraction
NCT07905105, Phase 1, Phase 2, Recruiting, Cytogel Pharma, LLC
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. A Study of CYT-1010 in Healthy Volunteers and Participants With Acute Pain After Third Molar Extraction. Trials, record NCT07905105. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07905105
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- A Study of CYT-1010 in Healthy Volunteers and Participants With Acute Pain After Third Molar Extraction
- NCT number
- NCT07905105
- Status
- Recruiting
- Phases
- Phase 1, Phase 2
- Enrollment
- 32 participants, estimated
- Lead sponsor
- Cytogel Pharma, LLC
- Conditions
- Acute Postoperative Pain, Dental Pain
- Interventions
- CYT-1010, Placebo
- First posted
- 2026-10-29
- Last updated
- 2026-10-29
Source ClinicalTrials.gov
Registered outcomes21
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Number of Participants With Treatment-Emergent Adverse Events | From trial drug administration through Day 7 | |
| Primary | Sum of Pain Intensity Differences (SPID) Over 2 Hours (SPID2) in Dental Pain Participants | From pre-dose to 2 hours post-dose | SPID2 is the time-weighted SPID over 0-2 hours after receiving medication, derived from postoperative dental pain assessed on a 0-10 numerical rating scale (NRS). NRS is a categorical 0-10 pain rating scale wherein 0 is defined as "no pain" and 10 is the "pain as bad as you can imagine". Higher scores indicate a greater level of pain intensity. |
| Secondary | Maximum Observed Plasma Concentration (Cmax) of CYT-1010 | Pre-dose through 8 hours post-dose | |
| Secondary | Time to Cmax (Tmax) of CYT-1010 | Pre-dose through 8 hours post-dose | |
| Secondary | Area Under the Concentration-time Curve (AUC) From 0 to Last Measurable Concentration (AUC0-t) of CYT-1010 | Pre-dose through 8 hours post-dose | |
| Secondary | AUC From 0 to Infinity (AUC0-inf) of CYT-1010 | Pre-dose through 8 hours post-dose | |
| Secondary | Elimination Rate Constant (Kel) of CYT-1010 | Pre-dose through 8 hours post-dose | |
| Secondary | Apparent total body clearance (CL) of CYT-1010 | Pre-dose through 8 hours post-dose | |
| Secondary | Total Volume of Distribution (Vss) of CYT-1010 | Pre-dose through 8 hours post-dose | |
| Secondary | Elimination Half-life (T1/2) of CYT-1010 of CYT-1010 | Pre-dose through 8 hours post-dose |
1 to 10 of 21Source ClinicalTrials.gov
See all 21 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07905105
GET https://conductscience.org/api/trials/v1/NCT07905105/registered?page=2