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Trial · NCT07906262

Efficacy of Rimegepant 75 mg for the Acute Treatment of Migraine: a Bayesian Individual Participant Data Meta-analysis Standardized to Defined Target Populations

NCT07906262, Active not recruiting, Pfizer

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Efficacy of Rimegepant 75 mg for the Acute Treatment of Migraine: a Bayesian Individual Participant Data Meta-analysis Standardized to Defined Target Populations. Trials, record NCT07906262. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07906262

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Efficacy of Rimegepant 75 mg for the Acute Treatment of Migraine: a Bayesian Individual Participant Data Meta-analysis Standardized to Defined Target Populations
NCT number
NCT07906262
Status
Active not recruiting
Enrollment
1 participants, actual
Lead sponsor
Pfizer
Conditions
Migraine
Interventions
Rimegepant, Placebo
First posted
2026-10-30
Last updated
2026-10-30

Source ClinicalTrials.gov

Registered outcomes18

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryPain Freedom at 2 Hours Postdose2 hours after administration of study treatmentAverage treatment effect of rimegepant 75 mg relative to placebo on the proportion of participants who achieve pain freedom 2 hours after treatment of a moderate or severe migraine attack.
PrimaryFreedom From the Most Bothersome Symptom at 2 Hours Postdose2 hours after administration of study treatment
Average treatment effect of rimegepant 75 mg relative to placebo on the proportion of participants who are free from their prespecified most bothersome migraine-associated symptom 2 hours after treatment.
PrimaryPain Relief at 2 Hours Postdose2 hours after administration of study treatmentAverage treatment effect of rimegepant 75 mg relative to placebo on the proportion of participants achieving pain relief 2 hours after treatment of a moderate or severe migraine attack.
SecondaryPain Freedom at 1 Hour Postdose1 hour after administration of study treatmentAverage treatment effect of rimegepant 75 mg relative to placebo on the proportion of participants who achieve pain freedom 1 hour after treatment of a moderate or severe migraine attack.
SecondaryPain Relief at 1 Hour Postdose1 hour after administration of study treatmentAverage treatment effect of rimegepant 75 mg relative to placebo on the proportion of participants achieving pain relief 1 hour after treatment of a moderate or severe migraine attack.
SecondaryReturn to Normal Function at 1 Hour Postdose1 hour after administration of study treatmentAverage treatment effect of rimegepant 75 mg relative to placebo on the proportion of participants with normal function 1 hour after treatment.
SecondaryReturn to Normal Function at 2 Hours Postdose2 hours after administration of study treatmentAverage treatment effect of rimegepant 75 mg relative to placebo on the proportion of participants with normal function 2 hours after treatment.
SecondarySustained Pain Freedom From 2 to 24 Hours Postdose2 to 24 hours after administration of study treatmentAverage treatment effect of rimegepant 75 mg relative to placebo on the proportion of participants with sustained pain freedom from 2 through 24 hours after treatment.
SecondarySustained Pain Freedom From 2 to 48 Hours Postdose2 to 48 hours after administration of study treatmentAverage treatment effect of rimegepant 75 mg relative to placebo on the proportion of participants with sustained pain freedom from 2 through 48 hours after treatment.
SecondarySustained Pain Relief From 2 to 24 Hours Postdose2 to 24 hours after administration of study treatmentAverage treatment effect of rimegepant 75 mg relative to placebo on the proportion of participants with sustained pain relief from 2 through 24 hours after treatment.

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers0

The papers the trial lists on ClinicalTrials.gov.

None in this release.

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT07906262

GET https://conductscience.org/api/trials/v1/NCT07906262/registered