Trial · NCT07906301
Organoid Drug Sensitivity-Guided Therapy for Refractory Tumors
NCT07906301, Not applicable, Recruiting, Tianjin Medical University Second Hospital
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Organoid Drug Sensitivity-Guided Therapy for Refractory Tumors. Trials, record NCT07906301. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07906301
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Organoid Drug Sensitivity-Guided Therapy for Refractory Tumors
- NCT number
- NCT07906301
- Status
- Recruiting
- Phases
- Not applicable
- Enrollment
- 144 participants, estimated
- Lead sponsor
- Tianjin Medical University Second Hospital
- Conditions
- Refractory Tumors, Organoid
- Interventions
- Organoid drug sensitivity-guided treatment
- First posted
- 2026-10-30
- Last updated
- 2026-10-30
Source ClinicalTrials.gov
Registered outcomes2
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Objective Response Rate (ORR) | From first dose until disease progression or death (up to 24 months) | Percentage of evaluable participants with complete response (CR) or partial response (PR) assessed by RECIST 1.1. ORR = (CR + PR) / total evaluable participants × 100%, with 95% confidence interval. |
| Secondary | Sensitivity, Specificity, and Accuracy of Organoid Drug Sensitivity Model in Predicting Clinical Response | From first dose until disease progression or death (up to 24 months) | Concordance between patient-derived organoid (PDO) drug sensitivity results and actual clinical response. Sensitivity = TP / (TP + FN); Specificity = TN / (TN + FP); Accuracy = (TP + TN) / (TP + TN + FP + FN). TP = true positive; TN = true negative; FN = false negative; FP = false positive. 95% confidence intervals will be calculated. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07906301
GET https://conductscience.org/api/trials/v1/NCT07906301/registered