Trial · NCT07906327
Corneal Biomechanics and Stromal Tissue Characteristics in Patients Undergoing SMILE
NCT07906327, Not yet recruiting, Tongji University
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Corneal Biomechanics and Stromal Tissue Characteristics in Patients Undergoing SMILE. Trials, record NCT07906327. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07906327
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Corneal Biomechanics and Stromal Tissue Characteristics in Patients Undergoing SMILE
- NCT number
- NCT07906327
- Status
- Not yet recruiting
- Enrollment
- 200 participants, estimated
- Lead sponsor
- Tongji University
- Conditions
- Myopia
- Interventions
- SMILE
- First posted
- 2026-10-30
- Last updated
- 2026-11-04
Source ClinicalTrials.gov
Registered outcomes5
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Preoperative Stiffness Parameter at First Applanation (SP-A1) | Baseline, 1year | SP-A1 will be obtained from quality-accepted Corvis ST measurements of the primary study eye. The acquisition and repeat-measurement rules will be standardized before enrollment. The primary comparison will estimate the difference in baseline SP-A1 between the high-myopia and non-high-myopia groups. |
| Secondary | Preoperative Integrated Inverse Radius | Baseline, 1year | Integrated inverse radius will be obtained from quality-accepted Corvis ST measurements of the primary study eye and compared between the prespecified refractive groups. |
| Secondary | Change in SP-A1 From Baseline to 12 Months | Baseline, 1year | Change will be calculated as SP-A1 at 12 months after SMILE minus preoperative SP-A1 in the primary study eye. Associations with baseline clinical characteristics and surgical parameters will be examined using prespecified analyses. |
| Secondary | Manifest Refractive Spherical Equivalent at 12 Months | 1year | Manifest refractive spherical equivalent will be calculated as sphere plus one-half of cylinder, expressed in diopters, for the primary study eye. |
| Secondary | Early Postoperative Changes in SP-A1 | 1 and 3 months | Changes from preoperative SP-A1 will be calculated separately at 1 and 3 months after SMILE to characterize the early postoperative trajectory. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07906327
GET https://conductscience.org/api/trials/v1/NCT07906327/registered