Trial · NCT07907029
Transcutaneous Auricular Vagus Nerve Stimulation Combined With Lifestyle Intervention for Visceral Fat Reduction in Adults With Overweight or Obesity
NCT07907029, Not applicable, Not yet recruiting, Guangdong Provincial Hospital of Traditional Chinese Medicine
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Transcutaneous Auricular Vagus Nerve Stimulation Combined With Lifestyle Intervention for Visceral Fat Reduction in Adults With Overweight or Obesity. Trials, record NCT07907029. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07907029
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Transcutaneous Auricular Vagus Nerve Stimulation Combined With Lifestyle Intervention for Visceral Fat Reduction in Adults With Overweight or Obesity
- NCT number
- NCT07907029
- Status
- Not yet recruiting
- Phases
- Not applicable
- Enrollment
- 50 participants, estimated
- Lead sponsor
- Guangdong Provincial Hospital of Traditional Chinese Medicine
- Conditions
- Overweight, Obesity
- Interventions
- transcutaneous auricular vagus nerve stimulation (taVNS), Standardized lifestyle program (calorie-restricted diet plus aerobic exercise)
- First posted
- 2026-10-30
- Last updated
- 2026-10-30
Source ClinicalTrials.gov
Registered outcomes8
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change in visceral fat index (VFI) | Baseline (week 0) and post-intervention (week 4) | VFI is assessed by bioelectrical impedance analysis (BCA-2A, Tsinghua Tongfang, China), and the outcome is the within-participant change from baseline to post-intervention. |
| Secondary | Change in body weight | Baseline (week 0) and post-intervention (week 4) | Body weight is measured with participants in light clothing without shoes, and the outcome is the within-participant change in body weight (kg) from baseline to post-intervention, compared between groups. |
| Secondary | Change in body mass index (BMI) | Baseline (week 0) and post-intervention (week 4) | BMI is calculated as body weight (kg) divided by height (m) squared, and the outcome is the within-participant change in BMI (kg/m2) from baseline to post-intervention, compared between groups. |
| Secondary | Change in body fat percentage (BFP) | Baseline (week 0) and post-intervention (week 4) | Body composition is assessed by bioelectrical impedance analysis (BCA-2A, Tsinghua Tongfang, China), and the outcome is the within-participant change in body fat percentage (%) from baseline to post-intervention, compared between groups. |
| Secondary | Group-by-time change in thalamocortical functional connectivity | Baseline (week 0) and post-intervention (week 4) | Thalamocortical functional connectivity is computed from resting-state fMRI data using the AAL3 atlas, and the outcome is the group-by-time change in thalamocortical connectivity from baseline to post-intervention. |
| Secondary | Change in effective (directed) connectivity among network nodes | Baseline (week 0) and post-intervention (week 4) | Effective (directed) connectivity among the nodes showing significant connectivity changes is estimated from resting-state fMRI, and the outcome is the change in directed connectivity from baseline to post-intervention. |
| Secondary | Change in global and nodal topological properties of whole-brain functional networks | Baseline (week 0) and post-intervention (week 4) | Global (clustering coefficient, shortest path length) and nodal (nodal degree, nodal efficiency) topological properties of whole-brain functional networks are derived from resting-state fMRI using the Schaefer-400 atlas, and the outcome is the change in each network property from baseline to post-intervention. |
| Secondary | Partial correlation coefficient between changes in brain network measures and changes in obesity-related indicators | Baseline (week 0) and post-intervention (week 4) | For brain network measures showing significant between-group differences in change, the partial correlation coefficient between the change in each brain network measure and the change in each obesity-related indicator (visceral fat index, body weight, BMI, body fat percentage) will be computed within the taVNS group, adjusting for relevant baseline covariates. Unit of measure: correlation coefficient (range -1 to 1). |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07907029
GET https://conductscience.org/api/trials/v1/NCT07907029/registered