Trial · NCT07907276
Early Switch in Moderate ARDS
NCT07907276, Not yet recruiting, University of Thessaly
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Early Switch in Moderate ARDS. Trials, record NCT07907276. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07907276
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Early Switch in Moderate ARDS
- NCT number
- NCT07907276
- Status
- Not yet recruiting
- Enrollment
- 30 participants, estimated
- Lead sponsor
- University of Thessaly
- Conditions
- Acute Respiratory Distress Syndrome (ARDS)
- Interventions
- Protocolized Transition From Controlled to Assisted Mechanical Ventilation
- First posted
- 2026-10-30
- Last updated
- 2026-10-30
Source ClinicalTrials.gov
Registered outcomes10
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Difference in Respiratory Mechanics between succesfull and failed transition using a pneumotachograph | During the first thirty minutes of assisted ventilation. | The investigator will measure the respiratory mechanics at baseline, after the first five minutes of assisted ventilation and at 30 minutes of assisted ventilation. We will measure respiratory rate (breaths per minute). |
| Primary | Difference in Respiratory Mechanics between succesfull and failed transition using a pneumotachograph | During the first thirty minutes of assisted ventilation. | The investigator will measure the respiratory mechanics at baseline, after the first five minutes of assisted ventilation and at 30 minutes of assisted ventilation. The measured variables will include the lung elastance, the chest wall elastance and the total respiratory system elastance (all measured in cmH₂O/L). |
| Primary | Difference in Respiratory Mechanics between succesfull and failed transition using a pneumotachograph | During the first thirty minutes of assisted ventilation. | The investigator will measure the respiratory mechanics at baseline, after the first five minutes of assisted ventilation and at 30 minutes of assisted ventilation. The measured variables will include the transpulmonary pressure, which is measured in cmH₂O. During the baseline measurement both statics and dynamics measurements will be calculated, whereas during the assisted phase the investigator will include only the dynamic measurements. |
| Primary | Difference in Respiratory Mechanics between succesfull and failed transition using a pneumotachograph | During the first thirty minutes of assisted ventilation. | The investigator will measure the respiratory mechanics at baseline, after the first five minutes of assisted ventilation and at 30 minutes of assisted ventilation. We will measure tidal volume (mLs). |
| Secondary | Differences in electrical impedance tomography variables between successful and failed transition to assisted ventilation | During the first thirty minutes of assisted ventilation. | The investigator will measure the variation in the global inhomogeneity index derived by using electrical impedance tomography. |
| Secondary | Differences in electrical impedance tomography variables between successful and failed transition to assisted ventilation | During the first 30-minutes of assisted ventilation. | The investigator will measure the end-expiratory lung impedance, EELI, which is measured in ohms. |
| Secondary | Differences in electrical impedance tomography variables between successful and failed transition to assisted ventilation | During the first 30-minutes of assisted ventilation. | The investigator will measure the ventral to dorsal ratio using the electrical impedance tomography. |
| Secondary | Differences in electrical impedance tomography variables between successful and failed transition to assisted ventilation | During the first 30-minutes of assisted ventilation. | The investigator will measure the variation in the pendelluft phenomenon using the impedance amplitude values. |
| Secondary | Differences in respiratory effort between successful and failed transition to assisted ventilation | During the first 30-minutes of assisted ventilation. | The investigator will measure the differences in esophageal pressure swings, ΔPes in cmH₂O, between the beginning of the transition phase and at the final 5 minutes of the 30-minute trial. |
| Secondary | Differences in respiratory effort between successful and failed transition to assisted ventilation. | During the first 30-minutes of assisted ventilation. | The investigator will measure the differences in the esophageal pressure-time product measured in cmH₂O⋅s/min, between the beginning of the transition phase and at the final 5 minutes of the 30-minute trial. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07907276
GET https://conductscience.org/api/trials/v1/NCT07907276/registered