Trial · NCT07909642
Registered outcomes11
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
1 to 11 of 11
Download this page as JSON| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Any Return of Spontaneous Circulation | up to 1 day | Number and percentage of participants who achieve return of spontaneous circulation, defined as the presence of a palpable pulse lasting for at least 1 minute, regardless of whether it occurs before or after hospital arrival. |
| Secondary | Sustained Return of Spontaneous Circulation | up to 1 day | Number and percentage of participants who achieve sustained return of spontaneous circulation, defined as the presence of a palpable pulse lasting for at least 20 consecutive minutes, regardless of whether it occurs before or after hospital arrival. |
| Secondary | Prehospital Return of Spontaneous Circulation | up to 1 day | Number and percentage of participants who achieve return of spontaneous circulation before hospital arrival, defined as the presence of a palpable pulse lasting for at least 1 minute before arrival at the emergency department. |
| Secondary | Survival With Spontaneous Circulation at Emergency Department Arrival | up to 1 day | Number and percentage of participants who achieve return of spontaneous circulation before hospital arrival and retain spontaneous circulation at the time of arrival at the emergency department. |
| Secondary | Survival to Intensive Care Unit Admission | up to 1 month | Number and percentage of participants who achieve return of spontaneous circulation, remain sufficiently stable after emergency department resuscitation, and are admitted to an intensive care unit. |
| Secondary | Survival at 30 days | 1 month | The number and proportion of patients who are alive 30 days after enrollment will be recorded and compared between the TEE-guided CPR group and the conventional CPR group. |
| Secondary | Survival to Hospital Discharge | up to 1 year | Number and percentage of participants who survive the index hospitalization and are discharged alive to home, a rehabilitation facility, or another long-term care setting. |
| Secondary | Favorable Neurological Outcome at Hospital Discharge | up to 1 year | Number and percentage of participants with a favorable neurological outcome at hospital discharge, defined as a Cerebral Performance Category score of 1 or 2. |
| Secondary | Achieving EtCO₂ ≥20 mmHg During Prehospital CPR | up to 1 day | The proportion of participants who achieve an end-tidal carbon dioxide (EtCO₂) level of ≥20 mmHg at least once during prehospital CPR after randomization, based on valid capnography measurements. |
| Other | EtCO₂ trend during CPR | up to 1 day | End-tidal carbon dioxide (EtCO₂), measured in mmHg, will be recorded at 1-minute intervals during ongoing prehospital and in-hospital CPR, beginning after randomization. The time of emergency call receipt by the EMS dispatch center will be defined as time zero. Measurements will be included until return of spontaneous circulation (ROSC) or termination of resuscitation. EtCO₂ values will be aligned according to elapsed time from emergency call receipt and displayed as group-level trend graphs to compare the TEE-guided CPR and conventional CPR groups. |
| Other | TEE- and CPR-related adverse events | up to 1 year | TEE- and CPR-related adverse events will be recorded and compared between groups. Events include suspected or confirmed oropharyngeal, esophageal, or gastric perforation; clinically important upper gastrointestinal bleeding requiring hemostatic intervention; airway dislodgement or ventilation difficulty related to TEE insertion; clinically significant interruption of chest compressions related to TEE; rib fracture, pneumothorax, hemothorax, or other CPR-related traumatic injury; and any other adverse event judged by the investigators to be related to TEE or CPR. |
Source ClinicalTrials.govtrials-2026-11-12-0.5.0
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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