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Trial · NCT07909928

Biologic Augmentation of Osteochondral Allograft Transplantation in the Knee

NCT07909928, Not applicable, Not yet recruiting, University of Minnesota

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Biologic Augmentation of Osteochondral Allograft Transplantation in the Knee. Trials, record NCT07909928. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07909928

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Biologic Augmentation of Osteochondral Allograft Transplantation in the Knee
NCT number
NCT07909928
Status
Not yet recruiting
Phases
Not applicable
Enrollment
10 participants, estimated
Lead sponsor
University of Minnesota
Conditions
Osteochondral Defect, Articular Cartilage Defect
Interventions
Biologically Augmented Osteochondral Allograft Transplantation
First posted
2026-11-02
Last updated
2026-11-02

Source ClinicalTrials.gov

Registered outcomes19

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryOsteochondral Allograft Incorporation Assessed by MRI6 months after surgery
Osteochondral allograft incorporation will be assessed using magnetic resonance imaging (MRI) at 6 months after surgery. MRI findings will be evaluated using the Osteochondral Allograft MRI Scoring System (OCAMRISS) and other radiographic indicators of graft incorporation. Results will be summarized descriptively.
SecondaryOsteochondral Allograft Incorporation at 12 Weeks12 weeks after surgery
Osteochondral allograft incorporation will be assessed using MRI at 12 weeks after surgery. MRI findings will be evaluated using OCAMRISS and other radiographic indicators of graft incorporation and summarized descriptively.
SecondaryOsteochondral Allograft Incorporation at 12 Months12 months after surgery, if clinically indicated
Additional MRI evaluation will be performed at 12 months for participants with incomplete graft incorporation at the 6-month assessment. Graft incorporation will be assessed using OCAMRISS and other MRI indicators of graft healing.
SecondaryChange in Knee Injury and Osteoarthritis Outcome Score (KOOS)Baseline, 1 week, 6 weeks, 12 weeks, 6 months, and 1 year after surgery
Patient-reported knee symptoms and function will be evaluated using the Knee Injury and Osteoarthritis Outcome Score (KOOS) at baseline and scheduled postoperative follow-up visits. Changes in KOOS scores over time will be summarized descriptively.
SecondaryChange in Knee Injury and Osteoarthritis Outcome Score (KOOS)Baseline
Patient-reported knee symptoms and function will be evaluated using the Knee Injury and Osteoarthritis Outcome Score (KOOS) at baseline and scheduled postoperative follow-up visits. Changes in KOOS scores over time will be summarized descriptively.
SecondaryChange in Knee Injury and Osteoarthritis Outcome Score (KOOS)1 week
Patient-reported knee symptoms and function will be evaluated using the Knee Injury and Osteoarthritis Outcome Score (KOOS) at baseline and scheduled postoperative follow-up visits. Changes in KOOS scores over time will be summarized descriptively.
SecondaryChange in Knee Injury and Osteoarthritis Outcome Score (KOOS)6 weeks
Patient-reported knee symptoms and function will be evaluated using the Knee Injury and Osteoarthritis Outcome Score (KOOS) at baseline and scheduled postoperative follow-up visits. Changes in KOOS scores over time will be summarized descriptively.
SecondaryChange in Knee Injury and Osteoarthritis Outcome Score (KOOS)12 weeks
Patient-reported knee symptoms and function will be evaluated using the Knee Injury and Osteoarthritis Outcome Score (KOOS) at baseline and scheduled postoperative follow-up visits. Changes in KOOS scores over time will be summarized descriptively.
SecondaryChange in Knee Injury and Osteoarthritis Outcome Score (KOOS)6 months
Patient-reported knee symptoms and function will be evaluated using the Knee Injury and Osteoarthritis Outcome Score (KOOS) at baseline and scheduled postoperative follow-up visits. Changes in KOOS scores over time will be summarized descriptively.
SecondaryChange in Knee Injury and Osteoarthritis Outcome Score (KOOS)1 year after surgery
Patient-reported knee symptoms and function will be evaluated using the Knee Injury and Osteoarthritis Outcome Score (KOOS) at baseline and scheduled postoperative follow-up visits. Changes in KOOS scores over time will be summarized descriptively.

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers0

The papers the trial lists on ClinicalTrials.gov.

None in this release.

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT07909928

GET https://conductscience.org/api/trials/v1/NCT07909928/registered