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Trial · NCT07910266

Impact of Egg-Based and Cell-Based Vaccine Platforms on Immune Responses to Repeated Influenza Vaccination

NCT07910266, Phase 4, Recruiting, University of Missouri-Columbia

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Impact of Egg-Based and Cell-Based Vaccine Platforms on Immune Responses to Repeated Influenza Vaccination. Trials, record NCT07910266. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07910266

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Impact of Egg-Based and Cell-Based Vaccine Platforms on Immune Responses to Repeated Influenza Vaccination
NCT number
NCT07910266
Status
Recruiting
Phases
Phase 4
Enrollment
220 participants, estimated
Lead sponsor
University of Missouri-Columbia
Conditions
Immunology
Interventions
Egg-Based Inactivated Influenza Vaccine, Cell-Based Inactivated Influenza Vaccine
First posted
2026-11-02
Last updated
2026-11-02

Source ClinicalTrials.gov

Registered outcomes2

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryChange from Baseline in Hemagglutination Inhibition (HAI) Antibody Geometric Mean Titers at 1 Month After the Second VaccinationBefore the first vaccination and 1 month after the second vaccination.
Hemagglutination inhibition (HAI) antibody titers against the prespecified influenza vaccine strains will be measured in serum samples using the HAI assay. Changes in HAI antibody geometric mean titers from baseline before the first vaccination to 1 month after the second vaccination will be compared among participants receiving four vaccination regimens: egg-egg, egg-cell, cell-egg, and cell-cell.
SecondaryChange from Baseline in Hemagglutination Inhibition (HAI) Antibody Geometric Mean Titers at 1 Month After the First VaccinationBefore the first vaccination and 1 month after the first vaccination.
Hemagglutination inhibition (HAI) antibody titers against the prespecified influenza vaccine strains will be measured in serum samples using the HAI assay. Changes in HAI antibody geometric mean titers from baseline before the first vaccination to 1 month after the first vaccination will be compared among participants in the four vaccination regimens, as appropriate to their assigned vaccination sequence.

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers17

The papers the trial lists on ClinicalTrials.gov.

PMIDListed asSource
24667168BACKGROUNDPubMed
30561688BACKGROUNDPubMed
31201055BACKGROUNDPubMed
31445771BACKGROUNDPubMed
32253431BACKGROUNDPubMed
33400775BACKGROUNDPubMed
35055642BACKGROUNDPubMed
35137512BACKGROUNDPubMed
36320195BACKGROUNDPubMed
37897009BACKGROUNDPubMed

1 to 10 of 17

See all 17 papers

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT07910266

GET https://conductscience.org/api/trials/v1/NCT07910266/registered