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Trial · NCT07910357

High-flow Nasal Cannula Oxygen Therapy Versus Conventional Oxygen Therapy in Children High-altitude Pulmonary Edema

NCT07910357, Not applicable, Not yet recruiting, Ye Fan

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. High-flow Nasal Cannula Oxygen Therapy Versus Conventional Oxygen Therapy in Children High-altitude Pulmonary Edema. Trials, record NCT07910357. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07910357

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
High-flow Nasal Cannula Oxygen Therapy Versus Conventional Oxygen Therapy in Children High-altitude Pulmonary Edema
NCT number
NCT07910357
Status
Not yet recruiting
Phases
Not applicable
Enrollment
116 participants, estimated
Lead sponsor
Ye Fan
Conditions
High-altitude Pulmonary Edema
Interventions
High-flow Nasal Cannula Oxygen Therapy (HFNC)
First posted
2026-11-02
Last updated
2026-11-02

Source ClinicalTrials.gov

Registered outcomes5

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryProportion of treatment failureFrom date of randomization until the time of first documented treatment failure from any cause, or until hospital discharge, assessed up to 5 days
Treatment failure: defined as the proportion of children who still cannot maintain target oxygen saturation or present with severe respiratory distress after standardized optimization of current oxygen-therapy parameters to the maximum recommended intensity, requiring escalation to non-invasive positive-pressure ventilation or invasive mechanical ventilation, or manifesting significant intolerance to the assigned oxygen therapy.
SecondaryTime to weaning off supplemental oxygenFrom date of randomization to oxygen therapy completion (oxygen weaning),an average of 3-5 daysHours from randomization to successful weaning to room air
SecondaryNet change in imaging Pulmonary Edema ScoreDay 3 post-randomizationChange in imaging Pulmonary Edema Score from baseline to Day 3 post-randomization
SecondaryEvolvement of SpO2From enrollment to treatment completion, an average of 3-5 days
SpO2 is the percentage of oxygen-saturated hemoglobin in the blood, indicating how well oxygen is being delivered throughout the body. It was measured non-invasively using a pulse oximeter, a small device placed on a participant's fingertip, which uses light to estimate blood oxygen levels.
SecondaryIncidence of oxygen therapy-related complicationsFrom randomization to discharge, assessed up to about 5 daysIncidence of oxygen therapy-related complications during hospital stay

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers7

The papers the trial lists on ClinicalTrials.gov.

PMIDListed asSource
11990106BACKGROUNDPubMed
20417340BACKGROUNDPubMed
29470103BACKGROUNDPubMed
35384735BACKGROUNDPubMed
35707984BACKGROUNDPubMed
36562650BACKGROUNDPubMed
39235690BACKGROUNDPubMed

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT07910357

GET https://conductscience.org/api/trials/v1/NCT07910357/registered