Trial · NCT07911007
Differentiating Heart Disease Between Adult-onset Autoimmune and Type 2 Diabetes
NCT07911007, Not applicable, Recruiting, University of Roma La Sapienza
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Differentiating Heart Disease Between Adult-onset Autoimmune and Type 2 Diabetes. Trials, record NCT07911007. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07911007
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Differentiating Heart Disease Between Adult-onset Autoimmune and Type 2 Diabetes
- NCT number
- NCT07911007
- Status
- Recruiting
- Phases
- Not applicable
- Enrollment
- 200 participants, estimated
- Lead sponsor
- University of Roma La Sapienza
- Conditions
- Diabete Mellitus, Autoimmune Diabetes, Latent Autoimmune Diabetes in Adult (LADA), Type 2 Diabetes, Heart Disease, Cardiometabolic Diseases, Cardiomyopathy, Diabetic
- Interventions
- Cardiac Magnetic Resonance
- First posted
- 2026-11-02
- Last updated
- 2026-11-02
Source ClinicalTrials.gov
Registered outcomes8
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Difference between LADA and T2D in the distribution in the identified clusters of diabetic heart disease | Baseline, pre-procedure | Cluster analysis based on measures of cardiac geometry and function derived from cardiac imaging will be used to define clusters of cardiac phenotypes. Differences in the distribution of groups in cardiac clusters will be tested |
| Secondary | Differences in circulating markers of metabolic and cardiovascular health between groups | Baseline, pre-procedure | |
| Secondary | Relationship of the circulating markers of metabolic and cardiovascular health with cardiac structure and function evaluated by cardiac imaging | Baseline, pre-procedure | |
| Secondary | Relationship between small nerve fibers damage with cardiac structure and function | Baseline, pre-procedure | Relationship between markers of small nerve fibers damage derived from corneal confocal microscopy and from cardiac autonomic reflex tests with cardiac structure and function evaluated by cardiac imaging |
| Secondary | Differences in cardiac autoimmunity between groups | Baseline, pre-procedure | Differences in the prevalence and levels of cardiac autoantibodies and in genetic predisposition to autoimmune diabetes between groups and their relationship with cardiac structure and function evaluated by cardiac imaging |
| Other | Differences in extracellular vescicles (EV) and markers of inflammasome activation between groups | Baseline, pre-procedure | |
| Other | Relationship of different EV and inflammasome profiles with cardiac structure and function evaluated by cardiac imaging | Baseline, pre-procedure | |
| Other | Longitudinal changes of cardiac contraction, geometry and coronary artery microcirculation, in relation to metabolic profile and inflammasome markers. | Through study completion, an average of 2.5 years |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07911007
GET https://conductscience.org/api/trials/v1/NCT07911007/registered