Trial · NCT07912437
Diaphragm Ultrasound and Neuromuscular Monitoring for Predicting Early Respiratory Events After Extubation
NCT07912437, Not yet recruiting, Mustafa Duran
3 sourcestrials-2026-11-12-0.4.0
Cite this record
ConductScience Library. Diaphragm Ultrasound and Neuromuscular Monitoring for Predicting Early Respiratory Events After Extubation. Trials, record NCT07912437. Release trials-2026-11-12-0.4.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07912437
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Diaphragm Ultrasound and Neuromuscular Monitoring for Predicting Early Respiratory Events After Extubation
- NCT number
- NCT07912437
- Status
- Not yet recruiting
- Enrollment
- 100 participants, estimated
- Lead sponsor
- Mustafa Duran
- Conditions
- Residual Neuromuscular Blockade, Diaphragm Dysfunction, Postoperative Pulmonary Complications, Airway Extubation
- Interventions
- Diaphragm ultrasonography4
- First posted
- 2026-11-03
- Last updated
- 2026-11-03
Source ClinicalTrials.gov
Registered outcomes7
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Incidence of early postoperative respiratory events | From tracheal extubation until discharge from the post-anesthesia care unit (PACU), assessed up to 2 hours | Composite of any of the following: SpO₂ \< 92% lasting at least 30 seconds; airway obstruction requiring jaw thrust; need for mask ventilation; laryngospasm; apnea (at least 15 seconds) or hypoventilation (respiratory rate \< 8/min for at least 1 minute); need for non-invasive ventilation; reintubation. |
| Secondary | Predictive accuracy of diaphragm thickening fraction | Diaphragm measured immediately before tracheal extubation (T2); respiratory events assessed from extubation until PACU discharge, up to 2 hours | Area under the ROC curve, sensitivity, specificity and optimal cut-off of DTF measured before extubation for predicting early respiratory events. |
| Secondary | Predictive accuracy of diaphragm excursion | Diaphragm measured immediately before tracheal extubation (T2); respiratory events assessed from extubation until PACU discharge, up to 2 hours | Area under the ROC curve, sensitivity, specificity and optimal cut-off of diaphragm excursion (cm) measured before extubation for predicting early respiratory events. |
| Secondary | Change in diaphragm thickening fraction from baseline | Before induction (T0) and before extubation (T2) | Percentage change in DTF before extubation compared with the pre-induction value. |
| Secondary | Diaphragm parameters across time points | Before induction (T0), 5 minutes after induction (T1), before extubation (T2), 30 minutes after extubation (T3) | Diaphragm thickness, DTF (%) and excursion (cm) at four time points. |
| Secondary | Correlation between TOF ratio and diaphragm parameters | Immediately before tracheal extubation | Correlation coefficient between the TOF ratio at extubation and DTF and diaphragm excursion before extubation. |
| Secondary | Incidence of individual respiratory events | From tracheal extubation until discharge from the post-anesthesia care unit (PACU), assessed up to 2 hours | Incidence of each component of the primary composite outcome. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Source
- Release
- trials-2026-11-12-0.4.0
- Release manifest SHA-256
- 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4
- Registry capture
- 2026-11-12
- Results copy, AACT
- 2026-03-23
- NIH clinical studies file
- 2026-11-13
Source ClinicalTrials.gov
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNone stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07912437
GET https://conductscience.org/api/trials/v1/NCT07912437/registered